Enhancement of Vaccine-Induced T-Cell Responses by PD-L1 Blockade in Calves

Interactions between programmed death 1 (PD-1) and PD-ligand 1 (PD-L1) cause functional exhaustion of T cells by inducing inhibitory signals, thereby attenuating effector functions of T cells. We have developed an anti-bovine PD-L1 blocking antibody (Ab) and have demonstrated that blockade of the in...

Descripción completa

Detalles Bibliográficos
Autores principales: Okagawa, Tomohiro, Konnai, Satoru, Nakamura, Hayato, Ganbaatar, Otgontuya, Sajiki, Yamato, Watari, Kei, Noda, Haruka, Honma, Mitsuru, Kato, Yukinari, Suzuki, Yasuhiko, Maekawa, Naoya, Murata, Shiro, Ohashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051159/
https://www.ncbi.nlm.nih.gov/pubmed/36992143
http://dx.doi.org/10.3390/vaccines11030559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051159/
https://www.ncbi.nlm.nih.gov/pubmed/36992143
http://dx.doi.org/10.3390/vaccines11030559

Ejemplares similares