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Enhancement of Vaccine-Induced T-Cell Responses by PD-L1 Blockade in Calves

Interactions between programmed death 1 (PD-1) and PD-ligand 1 (PD-L1) cause functional exhaustion of T cells by inducing inhibitory signals, thereby attenuating effector functions of T cells. We have developed an anti-bovine PD-L1 blocking antibody (Ab) and have demonstrated that blockade of the in...

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Detalles Bibliográficos
Autores principales:	Okagawa, Tomohiro, Konnai, Satoru, Nakamura, Hayato, Ganbaatar, Otgontuya, Sajiki, Yamato, Watari, Kei, Noda, Haruka, Honma, Mitsuru, Kato, Yukinari, Suzuki, Yasuhiko, Maekawa, Naoya, Murata, Shiro, Ohashi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051159/ https://www.ncbi.nlm.nih.gov/pubmed/36992143 http://dx.doi.org/10.3390/vaccines11030559

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