Cargando…
Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts
The bioaccessibility and bioavailability of phenolics compounds of two grape stem extracts with different composition were studied. High polymeric extract (HPE) presented a higher content of total phenolics (TPC), procyanidins, hemicelluloses, proteins, and ashes, whereas low procyanidin extract (LP...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051231/ https://www.ncbi.nlm.nih.gov/pubmed/36985434 http://dx.doi.org/10.3390/molecules28062461 |
_version_ | 1785014830700167168 |
---|---|
author | Nieto, Juan Antonio Fernández-Jalao, Irene Siles-Sánchez, María de las Nieves Santoyo, Susana Jaime, Laura |
author_facet | Nieto, Juan Antonio Fernández-Jalao, Irene Siles-Sánchez, María de las Nieves Santoyo, Susana Jaime, Laura |
author_sort | Nieto, Juan Antonio |
collection | PubMed |
description | The bioaccessibility and bioavailability of phenolics compounds of two grape stem extracts with different composition were studied. High polymeric extract (HPE) presented a higher content of total phenolics (TPC), procyanidins, hemicelluloses, proteins, and ashes, whereas low procyanidin extract (LPE) showed a higher fat, soluble sugars, and individual phenolic compounds content. Corresponding to its higher total phenolics content, HPE possesses a higher antioxidant activity (TEAC value). The digestion process reduced the antioxidant activity of the HPE up to 69%, due to the decrease of TPC (75%) with a significant loss of polymeric compounds. LPE antioxidant activity was stable, and TPC decreased by only 13% during the digestion process. Moreover, a higher antioxidant phenolic compounds bioavailability was shown in LPE in contrast to HPE. This behaviour was ascribed mainly to the negative interaction of polymeric fractions and the positive interaction of lipids with phenolic compounds. Therefore, this study highlights the convenience of carrying out previous studies to identify the better extraction conditions of individual bioavailable phenolic compounds with antioxidant activity, along with those constituents that could increase their bioaccessibility and bioavailability, such as lipids, although the role played by other components, such as hemicelluloses, cannot be ruled out. |
format | Online Article Text |
id | pubmed-10051231 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100512312023-03-30 Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts Nieto, Juan Antonio Fernández-Jalao, Irene Siles-Sánchez, María de las Nieves Santoyo, Susana Jaime, Laura Molecules Article The bioaccessibility and bioavailability of phenolics compounds of two grape stem extracts with different composition were studied. High polymeric extract (HPE) presented a higher content of total phenolics (TPC), procyanidins, hemicelluloses, proteins, and ashes, whereas low procyanidin extract (LPE) showed a higher fat, soluble sugars, and individual phenolic compounds content. Corresponding to its higher total phenolics content, HPE possesses a higher antioxidant activity (TEAC value). The digestion process reduced the antioxidant activity of the HPE up to 69%, due to the decrease of TPC (75%) with a significant loss of polymeric compounds. LPE antioxidant activity was stable, and TPC decreased by only 13% during the digestion process. Moreover, a higher antioxidant phenolic compounds bioavailability was shown in LPE in contrast to HPE. This behaviour was ascribed mainly to the negative interaction of polymeric fractions and the positive interaction of lipids with phenolic compounds. Therefore, this study highlights the convenience of carrying out previous studies to identify the better extraction conditions of individual bioavailable phenolic compounds with antioxidant activity, along with those constituents that could increase their bioaccessibility and bioavailability, such as lipids, although the role played by other components, such as hemicelluloses, cannot be ruled out. MDPI 2023-03-08 /pmc/articles/PMC10051231/ /pubmed/36985434 http://dx.doi.org/10.3390/molecules28062461 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nieto, Juan Antonio Fernández-Jalao, Irene Siles-Sánchez, María de las Nieves Santoyo, Susana Jaime, Laura Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title | Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title_full | Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title_fullStr | Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title_full_unstemmed | Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title_short | Implication of the Polymeric Phenolic Fraction and Matrix Effect on the Antioxidant Activity, Bioaccessibility, and Bioavailability of Grape Stem Extracts |
title_sort | implication of the polymeric phenolic fraction and matrix effect on the antioxidant activity, bioaccessibility, and bioavailability of grape stem extracts |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051231/ https://www.ncbi.nlm.nih.gov/pubmed/36985434 http://dx.doi.org/10.3390/molecules28062461 |
work_keys_str_mv | AT nietojuanantonio implicationofthepolymericphenolicfractionandmatrixeffectontheantioxidantactivitybioaccessibilityandbioavailabilityofgrapestemextracts AT fernandezjalaoirene implicationofthepolymericphenolicfractionandmatrixeffectontheantioxidantactivitybioaccessibilityandbioavailabilityofgrapestemextracts AT silessanchezmariadelasnieves implicationofthepolymericphenolicfractionandmatrixeffectontheantioxidantactivitybioaccessibilityandbioavailabilityofgrapestemextracts AT santoyosusana implicationofthepolymericphenolicfractionandmatrixeffectontheantioxidantactivitybioaccessibilityandbioavailabilityofgrapestemextracts AT jaimelaura implicationofthepolymericphenolicfractionandmatrixeffectontheantioxidantactivitybioaccessibilityandbioavailabilityofgrapestemextracts |