Cargando…
Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21(high) Cells In Vivo
P21 and p16 have been identified as inducers of senescence. Many transgenic mouse models have been developed to target cells expressing high levels of p16(Ink4a) (p16(high)) and investigate their potential contribution to tissue dysfunction in aging, obesity, and other pathological conditions. Howev...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051249/ https://www.ncbi.nlm.nih.gov/pubmed/36982640 http://dx.doi.org/10.3390/ijms24065565 |