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Treatment of Animal Tungiasis: What’s New?
In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051256/ https://www.ncbi.nlm.nih.gov/pubmed/36977143 http://dx.doi.org/10.3390/tropicalmed8030142 |
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author | dos Santos, Katharine Costa Brandão Guedes, Paula Elisa Teixeira, Jamille Bispo de Carvalho Harvey, Tatiani Vitor Carlos, Renata Santiago Alberto |
author_facet | dos Santos, Katharine Costa Brandão Guedes, Paula Elisa Teixeira, Jamille Bispo de Carvalho Harvey, Tatiani Vitor Carlos, Renata Santiago Alberto |
author_sort | dos Santos, Katharine Costa |
collection | PubMed |
description | In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis. |
format | Online Article Text |
id | pubmed-10051256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100512562023-03-30 Treatment of Animal Tungiasis: What’s New? dos Santos, Katharine Costa Brandão Guedes, Paula Elisa Teixeira, Jamille Bispo de Carvalho Harvey, Tatiani Vitor Carlos, Renata Santiago Alberto Trop Med Infect Dis Review In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis. MDPI 2023-02-27 /pmc/articles/PMC10051256/ /pubmed/36977143 http://dx.doi.org/10.3390/tropicalmed8030142 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review dos Santos, Katharine Costa Brandão Guedes, Paula Elisa Teixeira, Jamille Bispo de Carvalho Harvey, Tatiani Vitor Carlos, Renata Santiago Alberto Treatment of Animal Tungiasis: What’s New? |
title | Treatment of Animal Tungiasis: What’s New? |
title_full | Treatment of Animal Tungiasis: What’s New? |
title_fullStr | Treatment of Animal Tungiasis: What’s New? |
title_full_unstemmed | Treatment of Animal Tungiasis: What’s New? |
title_short | Treatment of Animal Tungiasis: What’s New? |
title_sort | treatment of animal tungiasis: what’s new? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051256/ https://www.ncbi.nlm.nih.gov/pubmed/36977143 http://dx.doi.org/10.3390/tropicalmed8030142 |
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