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Treatment of Animal Tungiasis: What’s New?

In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, a...

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Autores principales: dos Santos, Katharine Costa, Brandão Guedes, Paula Elisa, Teixeira, Jamille Bispo de Carvalho, Harvey, Tatiani Vitor, Carlos, Renata Santiago Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051256/
https://www.ncbi.nlm.nih.gov/pubmed/36977143
http://dx.doi.org/10.3390/tropicalmed8030142
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author dos Santos, Katharine Costa
Brandão Guedes, Paula Elisa
Teixeira, Jamille Bispo de Carvalho
Harvey, Tatiani Vitor
Carlos, Renata Santiago Alberto
author_facet dos Santos, Katharine Costa
Brandão Guedes, Paula Elisa
Teixeira, Jamille Bispo de Carvalho
Harvey, Tatiani Vitor
Carlos, Renata Santiago Alberto
author_sort dos Santos, Katharine Costa
collection PubMed
description In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis.
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spelling pubmed-100512562023-03-30 Treatment of Animal Tungiasis: What’s New? dos Santos, Katharine Costa Brandão Guedes, Paula Elisa Teixeira, Jamille Bispo de Carvalho Harvey, Tatiani Vitor Carlos, Renata Santiago Alberto Trop Med Infect Dis Review In tropical and subtropical countries, particularly in disadvantaged communities, tungiasis is a severe public health problem, which is often neglected by the authorities. The sand fleas Tunga penetrans, predominant in endemic areas, and Tunga trimamillata, whose cases in humans are less frequent, are the cause of this zoonosis. Domestic animals are potential reservoirs and disseminators of tungiasis, so controlling their infection would significantly advance the prevention of human cases. This literature review compiles the most recent studies and innovations in treating animal tungiasis. Studies of approaches to the treatment of animal tungiasis, as well as disease control and prevention, are described. Isoxazolines are highlighted as promising drugs to treat animal tungiasis, with high efficacy and pharmacological protection. The positive impacts of this discovery on public health are also discussed, since dogs are an essential risk factor for human tungiasis. MDPI 2023-02-27 /pmc/articles/PMC10051256/ /pubmed/36977143 http://dx.doi.org/10.3390/tropicalmed8030142 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
dos Santos, Katharine Costa
Brandão Guedes, Paula Elisa
Teixeira, Jamille Bispo de Carvalho
Harvey, Tatiani Vitor
Carlos, Renata Santiago Alberto
Treatment of Animal Tungiasis: What’s New?
title Treatment of Animal Tungiasis: What’s New?
title_full Treatment of Animal Tungiasis: What’s New?
title_fullStr Treatment of Animal Tungiasis: What’s New?
title_full_unstemmed Treatment of Animal Tungiasis: What’s New?
title_short Treatment of Animal Tungiasis: What’s New?
title_sort treatment of animal tungiasis: what’s new?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051256/
https://www.ncbi.nlm.nih.gov/pubmed/36977143
http://dx.doi.org/10.3390/tropicalmed8030142
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