Novel Indole-Tethered Chromene Derivatives: Synthesis, Cytotoxic Properties, and Key Computational Insights

Indole-tethered chromene derivatives were synthesised in a one-pot multicomponent reaction using N-alkyl-1H-indole-3-carbaldehydes, 5,5-dimethylcyclohexane-1,3-dione, and malononitrile, catalysed by DBU at 60–65 °C in a short reaction time. The benefits of the methodology include non-toxicity, an un...

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Detalles Bibliográficos
Autores principales: Malik, M. Shaheer, Ather, Hissana, Asif Ansari, Shaik Mohammad, Siddiqua, Ayesha, Jamal, Qazi Mohammad Sajid, Alharbi, Ali H., Al-Rooqi, Munirah M., Jassas, Rabab S., Hussein, Essam M., Moussa, Ziad, Obaid, Rami J., Ahmed, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051285/
https://www.ncbi.nlm.nih.gov/pubmed/36986433
http://dx.doi.org/10.3390/ph16030333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051285/
https://www.ncbi.nlm.nih.gov/pubmed/36986433
http://dx.doi.org/10.3390/ph16030333

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