Cargando…

Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos

SIMPLE SUMMARY: The Asian tiger mosquito, Aedes albopictus, is an invasive species that spreads disease and has recently become prevalent in its habitat due to human interference. In this study, we analyzed the genetic diversity and population structure of Ae. albopictus on the basis of two mitochon...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Jiyeong, Rahman, Md-Mafizur, Kim, Juil, Marcombe, Sébastien, Jung, Jongwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051289/
https://www.ncbi.nlm.nih.gov/pubmed/36975982
http://dx.doi.org/10.3390/insects14030297
_version_ 1785014849603895296
author Shin, Jiyeong
Rahman, Md-Mafizur
Kim, Juil
Marcombe, Sébastien
Jung, Jongwoo
author_facet Shin, Jiyeong
Rahman, Md-Mafizur
Kim, Juil
Marcombe, Sébastien
Jung, Jongwoo
author_sort Shin, Jiyeong
collection PubMed
description SIMPLE SUMMARY: The Asian tiger mosquito, Aedes albopictus, is an invasive species that spreads disease and has recently become prevalent in its habitat due to human interference. In this study, we analyzed the genetic diversity and population structure of Ae. albopictus on the basis of two mitochondrial genes (cytochrome oxidase subunit 1, COI and NADH dehydrogenase 5, ND5) and sixteen polymorphic microsatellites sourced from localities in Republic of Korea (hereafter Korea), Japan, and Laos. Mitochondrial analysis showed that the genetic diversity of the Korean and Japanese populations was low, while the Laos population did not share haplotypes with the former two groups, indicating that the Korean Ae. albopictus were not derived from the Laos population. On the basis of microsatellite results, the Korean, Japanese, and Laos populations showed higher diversity, although there were mixed groups, which implies that the Korean cluster is distinct. Continuous international trade and overseas travel require constant monitoring of species that can transmit mosquito-borne diseases. In addition, genetic studies would provide a useful basis for understanding the genetic status of vectors and for managing vector-borne diseases. ABSTRACT: Aedes albopictus is native to Southeast Asia and has emerged as a major vector for vector-borne diseases that are spreading rapidly worldwide. Recent studies have shown that Ae. albopictus populations have different genetic groups dependent on their thermal adaptations; however, studies on Korean populations are limited. In this study, we analyzed the genetic diversity and structure of two mitochondrial genes (COI and ND5) and sixteen microsatellites in mosquitoes inhabiting Korea, Japan, and Laos. The results indicate that the Korean population has low genetic diversity, with an independent cluster distinct from the Laos population. Mixed clusters have also been observed in the Korean population. On the basis of these findings, two hypotheses are proposed. First, certain Korean populations are native. Second, some subpopulations that descended from the metapopulation (East Asian countries) were introduced to Japan before migrating to Korea. Furthermore, we previously demonstrated that Ae. albopictus appears to have been imported to Korea. In conclusion, the dengue-virus-carrying mosquitoes could migrate to Korea from Southeast Asian epidemic regions, where they can survive during the severe winter months. The key findings can be used to establish an integrated pest management strategy based on population genetics for the Korean Ae. albopictus population.
format Online
Article
Text
id pubmed-10051289
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100512892023-03-30 Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos Shin, Jiyeong Rahman, Md-Mafizur Kim, Juil Marcombe, Sébastien Jung, Jongwoo Insects Article SIMPLE SUMMARY: The Asian tiger mosquito, Aedes albopictus, is an invasive species that spreads disease and has recently become prevalent in its habitat due to human interference. In this study, we analyzed the genetic diversity and population structure of Ae. albopictus on the basis of two mitochondrial genes (cytochrome oxidase subunit 1, COI and NADH dehydrogenase 5, ND5) and sixteen polymorphic microsatellites sourced from localities in Republic of Korea (hereafter Korea), Japan, and Laos. Mitochondrial analysis showed that the genetic diversity of the Korean and Japanese populations was low, while the Laos population did not share haplotypes with the former two groups, indicating that the Korean Ae. albopictus were not derived from the Laos population. On the basis of microsatellite results, the Korean, Japanese, and Laos populations showed higher diversity, although there were mixed groups, which implies that the Korean cluster is distinct. Continuous international trade and overseas travel require constant monitoring of species that can transmit mosquito-borne diseases. In addition, genetic studies would provide a useful basis for understanding the genetic status of vectors and for managing vector-borne diseases. ABSTRACT: Aedes albopictus is native to Southeast Asia and has emerged as a major vector for vector-borne diseases that are spreading rapidly worldwide. Recent studies have shown that Ae. albopictus populations have different genetic groups dependent on their thermal adaptations; however, studies on Korean populations are limited. In this study, we analyzed the genetic diversity and structure of two mitochondrial genes (COI and ND5) and sixteen microsatellites in mosquitoes inhabiting Korea, Japan, and Laos. The results indicate that the Korean population has low genetic diversity, with an independent cluster distinct from the Laos population. Mixed clusters have also been observed in the Korean population. On the basis of these findings, two hypotheses are proposed. First, certain Korean populations are native. Second, some subpopulations that descended from the metapopulation (East Asian countries) were introduced to Japan before migrating to Korea. Furthermore, we previously demonstrated that Ae. albopictus appears to have been imported to Korea. In conclusion, the dengue-virus-carrying mosquitoes could migrate to Korea from Southeast Asian epidemic regions, where they can survive during the severe winter months. The key findings can be used to establish an integrated pest management strategy based on population genetics for the Korean Ae. albopictus population. MDPI 2023-03-20 /pmc/articles/PMC10051289/ /pubmed/36975982 http://dx.doi.org/10.3390/insects14030297 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shin, Jiyeong
Rahman, Md-Mafizur
Kim, Juil
Marcombe, Sébastien
Jung, Jongwoo
Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title_full Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title_fullStr Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title_full_unstemmed Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title_short Genetic Diversity of Dengue Vector Aedes albopictus Collected from South Korea, Japan, and Laos
title_sort genetic diversity of dengue vector aedes albopictus collected from south korea, japan, and laos
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051289/
https://www.ncbi.nlm.nih.gov/pubmed/36975982
http://dx.doi.org/10.3390/insects14030297
work_keys_str_mv AT shinjiyeong geneticdiversityofdenguevectoraedesalbopictuscollectedfromsouthkoreajapanandlaos
AT rahmanmdmafizur geneticdiversityofdenguevectoraedesalbopictuscollectedfromsouthkoreajapanandlaos
AT kimjuil geneticdiversityofdenguevectoraedesalbopictuscollectedfromsouthkoreajapanandlaos
AT marcombesebastien geneticdiversityofdenguevectoraedesalbopictuscollectedfromsouthkoreajapanandlaos
AT jungjongwoo geneticdiversityofdenguevectoraedesalbopictuscollectedfromsouthkoreajapanandlaos