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Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects

Baccharis is one of the largest genera of Asteraceae and its species are used in folk medicine for several medicinal purposes due to the presence of bioactive compounds. We investigated the phytochemical composition of polar extracts of B. sphenophylla. Using chromatographic procedures, diterpenoids...

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Autores principales: Retamozo, Marcela H., Silva, Christian C., Tamayose, Cinthia I., Carvalho, Juliana C. S., Romoff, Paulete, Fávero, Oriana A., Ferreira, Marcelo J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051307/
https://www.ncbi.nlm.nih.gov/pubmed/36986952
http://dx.doi.org/10.3390/plants12061262
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author Retamozo, Marcela H.
Silva, Christian C.
Tamayose, Cinthia I.
Carvalho, Juliana C. S.
Romoff, Paulete
Fávero, Oriana A.
Ferreira, Marcelo J. P.
author_facet Retamozo, Marcela H.
Silva, Christian C.
Tamayose, Cinthia I.
Carvalho, Juliana C. S.
Romoff, Paulete
Fávero, Oriana A.
Ferreira, Marcelo J. P.
author_sort Retamozo, Marcela H.
collection PubMed
description Baccharis is one of the largest genera of Asteraceae and its species are used in folk medicine for several medicinal purposes due to the presence of bioactive compounds. We investigated the phytochemical composition of polar extracts of B. sphenophylla. Using chromatographic procedures, diterpenoids (ent-kaurenoic acid), flavonoids (hispidulin, eupafolin, isoquercitrin, quercitrin, biorobin, rutin, and vicenin-2), caffeic acid, and chlorogenic acid derivatives (5-O-caffeoylquinic acid and its methyl ester, 3,4-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid, and 3,5-di-O-caffeoylquinic acid and its methyl ester) were isolated from polar fractions and are described. The extract, polar fractions, and fifteen isolated compounds were evaluated in relation to radical scavenging activity using two assays. Chlorogenic acid derivatives and flavonols exhibited higher antioxidant effects, confirming that B. sphenophylla is an important source of phenolic compounds with antiradical properties.
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spelling pubmed-100513072023-03-30 Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects Retamozo, Marcela H. Silva, Christian C. Tamayose, Cinthia I. Carvalho, Juliana C. S. Romoff, Paulete Fávero, Oriana A. Ferreira, Marcelo J. P. Plants (Basel) Article Baccharis is one of the largest genera of Asteraceae and its species are used in folk medicine for several medicinal purposes due to the presence of bioactive compounds. We investigated the phytochemical composition of polar extracts of B. sphenophylla. Using chromatographic procedures, diterpenoids (ent-kaurenoic acid), flavonoids (hispidulin, eupafolin, isoquercitrin, quercitrin, biorobin, rutin, and vicenin-2), caffeic acid, and chlorogenic acid derivatives (5-O-caffeoylquinic acid and its methyl ester, 3,4-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid, and 3,5-di-O-caffeoylquinic acid and its methyl ester) were isolated from polar fractions and are described. The extract, polar fractions, and fifteen isolated compounds were evaluated in relation to radical scavenging activity using two assays. Chlorogenic acid derivatives and flavonols exhibited higher antioxidant effects, confirming that B. sphenophylla is an important source of phenolic compounds with antiradical properties. MDPI 2023-03-10 /pmc/articles/PMC10051307/ /pubmed/36986952 http://dx.doi.org/10.3390/plants12061262 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Retamozo, Marcela H.
Silva, Christian C.
Tamayose, Cinthia I.
Carvalho, Juliana C. S.
Romoff, Paulete
Fávero, Oriana A.
Ferreira, Marcelo J. P.
Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title_full Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title_fullStr Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title_full_unstemmed Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title_short Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
title_sort chemical constituents from leaves of baccharis sphenophylla (asteraceae) and their antioxidant effects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051307/
https://www.ncbi.nlm.nih.gov/pubmed/36986952
http://dx.doi.org/10.3390/plants12061262
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