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Design, Synthesis, and Neuroprotective Activity of Phenoxyindole Derivatives on Antiamyloid Beta (Aβ) Aggregation, Antiacetylcholinesterase, and Antioxidant Activities

In this investigation, a number of phenoxyindole derivatives were designed, synthesized, and tested for their neuroprotective ability on SK-N-SH cells against Aβ(42)-induced cell death and biologically specific activities involved in anti-Aβ aggregation, anti-AChE, and antioxidant effects. The propo...

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Detalles Bibliográficos
Autores principales: Laivut, Somjate, Moongkarndi, Primchanien, Kitphati, Worawan, Rukthong, Pattarawit, Sathirakul, Korbtham, Sripha, Kittisak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051485/
https://www.ncbi.nlm.nih.gov/pubmed/36986454
http://dx.doi.org/10.3390/ph16030355