Cargando…

Identification of Plant Peptides as Novel Inhibitors of Orthohepevirus A (HEV) Capsid Protein by Virtual Screening

Hepatitis E virus (HEV) is the notable causative agent of acute and chronic hepatic, renal, pancreatic, neurological, and hematopoietic blood cell infections with high risk in immunocompromised patients. Hepatic failure is mostly documented among adults, pregnant women, and patients with preexisting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mustafa, Ghulam, Mahrosh, Hafiza Salaha, Attique, Syed Awais, Arif, Rawaba, Farah, Mohammad Abul, Al-Anazi, Khalid Mashay, Ali, Sajad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051542/ https://www.ncbi.nlm.nih.gov/pubmed/36985647 http://dx.doi.org/10.3390/molecules28062675

Ejemplares similares

Sequence and Structural Characterization of Toll-Like Receptor 6 from Human and Related Species
por: Mustafa, Ghulam, et al.
Publicado: (2021)

In Silico Characterization of Growth Differentiation Factors as Inhibitors of TNF-Alpha and IL-6 in Immune-Mediated Inflammatory Disease Rheumatoid Arthritis
por: Mustafa, Ghulam, et al.
Publicado: (2021)

Exploring the antihyperglycemic potential of tetrapeptides devised from AdMc1 via different receptor proteins inhibition using in silico approaches
por: Mustafa, Ghulam, et al.
Publicado: (2022)

In Silico Analysis of Honey Bee Peptides as Potential Inhibitors of Capripoxvirus DNA-Directed RNA Polymerase
por: Mustafa, Ghulam, et al.
Publicado: (2023)

Investigation of Hypoglycemic Peptides Derived from Conserved Regions of adMc1 to Reveal Their Antidiabetic Activities
por: Mahrosh, Hafiza Salaha, et al.
Publicado: (2021)

Molecular Docking and Simulation Studies of Antidiabetic Agents Devised from Hypoglycemic Polypeptide-P of Momordica charantia
por: Arif, Rawaba, et al.
Publicado: (2021)

The COVID-19 puzzle: a global nightmare
por: Mahrosh, Hafiza Salaha, et al.
Publicado: (2021)

An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals
por: Mahrosh, Hafiza Salaha, et al.
Publicado: (2021)

Investigation of Plant Antimicrobial Peptides against Selected Pathogenic Bacterial Species Using a Peptide-Protein Docking Approach
por: Mustafa, Ghulam, et al.
Publicado: (2022)

Identification of Peptides as Novel Inhibitors to Target IFN-γ, IL-3, and TNF-α in Systemic Lupus Erythematosus
por: Mustafa, Ghulam, et al.
Publicado: (2021)

Molecular Docking and Simulation-Binding Analysis of Plant Phytochemicals with the Hepatocellular Carcinoma Targets Epidermal Growth Factor Receptor and Caspase-9
por: Mustafa, Ghulam, et al.
Publicado: (2023)

Virtual screening of phytochemicals by targeting multiple proteins of severe acute respiratory syndrome coronavirus 2: Molecular docking and molecular dynamics simulation studies
por: Azeem, Muhammad, et al.
Publicado: (2022)

Bioremediation of Cadmium Toxicity in Wheat (Triticum aestivum L.) Plants Primed with L-Proline, Bacillus subtilis and Aspergillus niger
por: Bashir, Sarmad, et al.
Publicado: (2022)

Structure-based virtual screening of phytochemicals and repurposing of FDA approved antiviral drugs unravels lead molecules as potential inhibitors of coronavirus 3C-like protease enzyme
por: Bahadur Gurung, Arun, et al.
Publicado: (2020)

Indexing hematological and serum biochemical reference intervals of Himalayan snow trout, Schizothorax esocinus to instrument in health assessment
por: Reshi, Quseen Mushtaq, et al.
Publicado: (2023)

Integrative approach for validation of six important fish species inhabiting River Poonch of north-west Himalayan region (India)
por: Awas, Mohd, et al.
Publicado: (2023)

Comprehensive exploration of the anticancer activities of procaine and its binding with calf thymus DNA: a multi spectroscopic and molecular modelling study
por: Ali, Mohd. Sajid, et al.
Publicado: (2018)

Novel orthohepeviruses in wild rodents from São Paulo State, Brazil
por: de Souza, William Marciel, et al.
Publicado: (2018)

Orthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants
por: Wang, Bo, et al.
Publicado: (2020)

No Evidence for Orthohepevirus C in Archived Human Samples in Germany, 2000–2020
por: Faber, Mirko, et al.
Publicado: (2022)

In silico screening of FDA approved drugs reveals ergotamine and dihydroergotamine as potential coronavirus main protease enzyme inhibitors
por: Gurung, Arun Bahadur, et al.
Publicado: (2020)

Unravelling lead antiviral phytochemicals for the inhibition of SARS-CoV-2 M(pro) enzyme through in silico approach
por: Gurung, Arun Bahadur, et al.
Publicado: (2020)

The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

An Updated Review of Computer-Aided Drug Design and Its Application to COVID-19
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

Molecular docking and dynamics simulation study of bioactive compounds from Ficus carica L. with important anticancer drug targets
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

Molecular modelling studies unveil potential binding sites on human serum albumin for selected experimental and in silico COVID-19 drug candidate molecules
por: Gurung, Arun Bahadur, et al.
Publicado: (2022)

Viability RT-qPCR to Distinguish Between HEV and HAV With Intact and Altered Capsids
por: Randazzo, Walter, et al.
Publicado: (2018)

Update: proposed reference sequences for subtypes of hepatitis E virus (species Orthohepevirus A)
por: Smith, Donald B., et al.
Publicado: (2020)

Molecular docking elucidates the plausible mechanisms underlying the anticancer properties of acetyldigitoxigenin from Adenium obesum
por: Gurung, Arun Bahadur, et al.
Publicado: (2020)

Identification of SARS-CoV-2 inhibitors from extracts of Houttuynia cordata Thunb.
por: Bahadur Gurung, Arun, et al.
Publicado: (2021)

Fluorescent delivery vehicle containing cobalt oxide–umbelliferone nanoconjugate: DNA/protein interaction studies and anticancer activity on MF7 cancer cell line
por: Ali, Mohd Sajid, et al.
Publicado: (2019)

Artesunate induces substantial topological alterations in the SARS-CoV-2 Nsp1 protein structure
por: Gurung, Arun Bahadur, et al.
Publicado: (2022)

Transcriptome characterization of Larrea tridentata and identification of genes associated with phenylpropanoid metabolic pathways
por: Ali, Mohammad Ajmal, et al.
Publicado: (2022)

Unlocking the Therapeutic Potential of Stevia rebaudiana Bertoni: A Natural Antiglycating Agent and Non-Toxic Support for HDF Cell Health
por: Shahu, Rinkey, et al.
Publicado: (2023)

In Silico Method for the Screening of Phytochemicals against Methicillin-Resistant Staphylococcus Aureus
por: Tabassum, Riaz, et al.
Publicado: (2023)

Structural and functional insights into the major mutations of SARS-CoV-2 Spike RBD and its interaction with human ACE2 receptor
por: Gurung, Arun Bahadur, et al.
Publicado: (2022)

Multi-Targeted Approaches and Drug Repurposing Reveal Possible SARS-CoV-2 Inhibitors
por: Alanazi, Khalid Mashay, et al.
Publicado: (2021)

HEV-Capsid Protein Interacts With Cytochrome P4502C8 and Retinol-Binding Protein 4
por: Shen, Quan, et al.
Publicado: (2011)

More powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
por: De Colibus, Luigi, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6gn6nrdc4b30711pfdsab6t18n