Kynureninase Promotes Immunosuppression and Predicts Survival in Glioma Patients: In Silico Data Analyses of the Chinese Glioma Genome Atlas (CGGA) and of the Cancer Genome Atlas (TCGA)

Kynureninase (KYNU) is a kynurenine pathway (KP) enzyme that produces metabolites with immunomodulatory properties. In recent years, overactivation of KP has been associated with poor prognosis of several types of cancer, in particular by promoting the invasion, metastasis, and chemoresistance of ca...

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Detalles Bibliográficos
Autores principales: Pérez de la Cruz, Gonzalo, Pérez de la Cruz, Verónica, Navarro Cossio, Javier, Vázquez Cervantes, Gustavo Ignacio, Salazar, Aleli, Orozco Morales, Mario, Pineda, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051585/
https://www.ncbi.nlm.nih.gov/pubmed/36986469
http://dx.doi.org/10.3390/ph16030369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051585/
https://www.ncbi.nlm.nih.gov/pubmed/36986469
http://dx.doi.org/10.3390/ph16030369

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