Structural Complementarity of Bruton’s Tyrosine Kinase and Its Inhibitors for Implication in B-Cell Malignancies and Autoimmune Diseases

Bruton’s tyrosine kinase (BTK) is a critical component in B-cell receptor (BCR) signaling and is also expressed in haematogenic and innate immune cells. Inhibition of BTK hyperactivity is implicated in B-cell malignancies and autoimmune diseases. This review derives the structural complementarity of...

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Detalles Bibliográficos
Autores principales: Najmi, Asim, Thangavel, Neelaveni, Mohanan, Anugeetha Thacheril, Qadri, Marwa, Albratty, Mohammed, Ashraf, Safeena Eranhiyil, Saleh, Safaa Fathy, Nayeem, Maryam, Mohan, Syam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051736/
https://www.ncbi.nlm.nih.gov/pubmed/36986499
http://dx.doi.org/10.3390/ph16030400

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