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GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants

γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research st...

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Autores principales: Yuan, Ding, Wu, Xiaolei, Gong, Binbin, Huo, Ruixiao, Zhao, Liran, Li, Jingrui, Lü, Guiyun, Gao, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051757/
https://www.ncbi.nlm.nih.gov/pubmed/36984787
http://dx.doi.org/10.3390/metabo13030347
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author Yuan, Ding
Wu, Xiaolei
Gong, Binbin
Huo, Ruixiao
Zhao, Liran
Li, Jingrui
Lü, Guiyun
Gao, Hongbo
author_facet Yuan, Ding
Wu, Xiaolei
Gong, Binbin
Huo, Ruixiao
Zhao, Liran
Li, Jingrui
Lü, Guiyun
Gao, Hongbo
author_sort Yuan, Ding
collection PubMed
description γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance.
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spelling pubmed-100517572023-03-30 GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants Yuan, Ding Wu, Xiaolei Gong, Binbin Huo, Ruixiao Zhao, Liran Li, Jingrui Lü, Guiyun Gao, Hongbo Metabolites Review γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance. MDPI 2023-02-26 /pmc/articles/PMC10051757/ /pubmed/36984787 http://dx.doi.org/10.3390/metabo13030347 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yuan, Ding
Wu, Xiaolei
Gong, Binbin
Huo, Ruixiao
Zhao, Liran
Li, Jingrui
Lü, Guiyun
Gao, Hongbo
GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title_full GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title_fullStr GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title_full_unstemmed GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title_short GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
title_sort gaba metabolism, transport and their roles and mechanisms in the regulation of abiotic stress (hypoxia, salt, drought) resistance in plants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051757/
https://www.ncbi.nlm.nih.gov/pubmed/36984787
http://dx.doi.org/10.3390/metabo13030347
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