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GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants
γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research st...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051757/ https://www.ncbi.nlm.nih.gov/pubmed/36984787 http://dx.doi.org/10.3390/metabo13030347 |
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author | Yuan, Ding Wu, Xiaolei Gong, Binbin Huo, Ruixiao Zhao, Liran Li, Jingrui Lü, Guiyun Gao, Hongbo |
author_facet | Yuan, Ding Wu, Xiaolei Gong, Binbin Huo, Ruixiao Zhao, Liran Li, Jingrui Lü, Guiyun Gao, Hongbo |
author_sort | Yuan, Ding |
collection | PubMed |
description | γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance. |
format | Online Article Text |
id | pubmed-10051757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100517572023-03-30 GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants Yuan, Ding Wu, Xiaolei Gong, Binbin Huo, Ruixiao Zhao, Liran Li, Jingrui Lü, Guiyun Gao, Hongbo Metabolites Review γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance. MDPI 2023-02-26 /pmc/articles/PMC10051757/ /pubmed/36984787 http://dx.doi.org/10.3390/metabo13030347 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yuan, Ding Wu, Xiaolei Gong, Binbin Huo, Ruixiao Zhao, Liran Li, Jingrui Lü, Guiyun Gao, Hongbo GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title | GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title_full | GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title_fullStr | GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title_full_unstemmed | GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title_short | GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants |
title_sort | gaba metabolism, transport and their roles and mechanisms in the regulation of abiotic stress (hypoxia, salt, drought) resistance in plants |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051757/ https://www.ncbi.nlm.nih.gov/pubmed/36984787 http://dx.doi.org/10.3390/metabo13030347 |
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