Modification of the Linker Amino Acid in the Cell-Penetrating Peptide NickFect55 Leads to Enhanced pDNA Transfection for In Vivo Applications

Despite numerous efforts over the last three decades, nucleic acid-based therapeutics still lack delivery platforms in the clinical stage. Cell-penetrating peptides (CPPs) may offer solutions as potential delivery vectors. We have previously shown that designing a “kinked” structure in the peptide b...

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Detalles Bibliográficos
Autores principales: Härk, Heleri H., Porosk, Ly, de Mello, Lucas R., Arukuusk, Piret, da Silva, Emerson R., Kurrikoff, Kaido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051810/
https://www.ncbi.nlm.nih.gov/pubmed/36986744
http://dx.doi.org/10.3390/pharmaceutics15030883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051810/
https://www.ncbi.nlm.nih.gov/pubmed/36986744
http://dx.doi.org/10.3390/pharmaceutics15030883

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