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Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies

Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central nervous system micafungin concentrations. To a...

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Detalles Bibliográficos
Autores principales: De Rose, Domenico Umberto, Bersani, Iliana, Ronchetti, Maria Paola, Piersigilli, Fiammetta, Cairoli, Sara, Dotta, Andrea, Desai, Amit, Kovanda, Laura Lynn, Goffredo, Bianca Maria, Auriti, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051811/
https://www.ncbi.nlm.nih.gov/pubmed/36986569
http://dx.doi.org/10.3390/ph16030472