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Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies
Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central nervous system micafungin concentrations. To a...
Autores principales: | De Rose, Domenico Umberto, Bersani, Iliana, Ronchetti, Maria Paola, Piersigilli, Fiammetta, Cairoli, Sara, Dotta, Andrea, Desai, Amit, Kovanda, Laura Lynn, Goffredo, Bianca Maria, Auriti, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051811/ https://www.ncbi.nlm.nih.gov/pubmed/36986569 http://dx.doi.org/10.3390/ph16030472 |
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