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A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules

In this article, the performance of n-type junctionless (JL) double-gate (DG) MOSFET-based biosensors with and without gate stack (GS) has been studied. Here, the dielectric modulation (DM) method is applied to detect biomolecules in the cavity. The sensitivity of n-type JL-DM-DG-MOSFET and n-type J...

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Autores principales: Chowdhury, Dibyendu, De, Bishnu Prasad, Appasani, Bhargav, Singh, Navaneet Kumar, Kar, Rajib, Mandal, Durbadal, Bizon, Nicu, Thounthong, Phatiphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052121/
https://www.ncbi.nlm.nih.gov/pubmed/36991665
http://dx.doi.org/10.3390/s23062953
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author Chowdhury, Dibyendu
De, Bishnu Prasad
Appasani, Bhargav
Singh, Navaneet Kumar
Kar, Rajib
Mandal, Durbadal
Bizon, Nicu
Thounthong, Phatiphat
author_facet Chowdhury, Dibyendu
De, Bishnu Prasad
Appasani, Bhargav
Singh, Navaneet Kumar
Kar, Rajib
Mandal, Durbadal
Bizon, Nicu
Thounthong, Phatiphat
author_sort Chowdhury, Dibyendu
collection PubMed
description In this article, the performance of n-type junctionless (JL) double-gate (DG) MOSFET-based biosensors with and without gate stack (GS) has been studied. Here, the dielectric modulation (DM) method is applied to detect biomolecules in the cavity. The sensitivity of n-type JL-DM-DG-MOSFET and n-type JL-DM-GSDG-MOSFET-based biosensors have also been evaluated. The sensitivity (ΔV(th)) improved in JL-DM-GSDG MOSFET/JL-DM-DG-MOSFET-based biosensors for neutral/charged biomolecules is 116.66%/66.66% and 1165.78%/978.94%, respectively, compared with the previously reported results. The electrical detection of biomolecules is validated using the ATLAS device simulator. The noise and analog/RF parameters are compared between both biosensors. A lower threshold voltage is observed in the GSDG-MOSFET-based biosensor. The I(on)/I(off) ratio is higher for DG-MOSFET-based biosensors. The proposed GSDG-MOSFET-based biosensor demonstrates higher sensitivity than the DG-MOSFET-based biosensor. The GSDG-MOSFET-based biosensor is suitable for low-power, high-speed, and high sensitivity applications.
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spelling pubmed-100521212023-03-30 A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules Chowdhury, Dibyendu De, Bishnu Prasad Appasani, Bhargav Singh, Navaneet Kumar Kar, Rajib Mandal, Durbadal Bizon, Nicu Thounthong, Phatiphat Sensors (Basel) Article In this article, the performance of n-type junctionless (JL) double-gate (DG) MOSFET-based biosensors with and without gate stack (GS) has been studied. Here, the dielectric modulation (DM) method is applied to detect biomolecules in the cavity. The sensitivity of n-type JL-DM-DG-MOSFET and n-type JL-DM-GSDG-MOSFET-based biosensors have also been evaluated. The sensitivity (ΔV(th)) improved in JL-DM-GSDG MOSFET/JL-DM-DG-MOSFET-based biosensors for neutral/charged biomolecules is 116.66%/66.66% and 1165.78%/978.94%, respectively, compared with the previously reported results. The electrical detection of biomolecules is validated using the ATLAS device simulator. The noise and analog/RF parameters are compared between both biosensors. A lower threshold voltage is observed in the GSDG-MOSFET-based biosensor. The I(on)/I(off) ratio is higher for DG-MOSFET-based biosensors. The proposed GSDG-MOSFET-based biosensor demonstrates higher sensitivity than the DG-MOSFET-based biosensor. The GSDG-MOSFET-based biosensor is suitable for low-power, high-speed, and high sensitivity applications. MDPI 2023-03-08 /pmc/articles/PMC10052121/ /pubmed/36991665 http://dx.doi.org/10.3390/s23062953 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chowdhury, Dibyendu
De, Bishnu Prasad
Appasani, Bhargav
Singh, Navaneet Kumar
Kar, Rajib
Mandal, Durbadal
Bizon, Nicu
Thounthong, Phatiphat
A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title_full A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title_fullStr A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title_full_unstemmed A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title_short A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules
title_sort novel dielectric modulated gate-stack double-gate metal-oxide-semiconductor field-effect transistor-based sensor for detecting biomolecules
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052121/
https://www.ncbi.nlm.nih.gov/pubmed/36991665
http://dx.doi.org/10.3390/s23062953
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