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Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052127/ https://www.ncbi.nlm.nih.gov/pubmed/36976242 http://dx.doi.org/10.3390/md21030193 |
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author | Akram, Wasim Rihan, Mohd Ahmed, Sakeel Arora, Swamita Ahmad, Sameer Vashishth, Rahul |
author_facet | Akram, Wasim Rihan, Mohd Ahmed, Sakeel Arora, Swamita Ahmad, Sameer Vashishth, Rahul |
author_sort | Akram, Wasim |
collection | PubMed |
description | Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds’ cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed. |
format | Online Article Text |
id | pubmed-10052127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100521272023-03-30 Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry Akram, Wasim Rihan, Mohd Ahmed, Sakeel Arora, Swamita Ahmad, Sameer Vashishth, Rahul Mar Drugs Review Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds’ cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed. MDPI 2023-03-21 /pmc/articles/PMC10052127/ /pubmed/36976242 http://dx.doi.org/10.3390/md21030193 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Akram, Wasim Rihan, Mohd Ahmed, Sakeel Arora, Swamita Ahmad, Sameer Vashishth, Rahul Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title | Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title_full | Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title_fullStr | Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title_full_unstemmed | Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title_short | Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry |
title_sort | marine-derived compounds applied in cardiovascular diseases: submerged medicinal industry |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052127/ https://www.ncbi.nlm.nih.gov/pubmed/36976242 http://dx.doi.org/10.3390/md21030193 |
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