Cargando…

Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry

Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Akram, Wasim, Rihan, Mohd, Ahmed, Sakeel, Arora, Swamita, Ahmad, Sameer, Vashishth, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052127/
https://www.ncbi.nlm.nih.gov/pubmed/36976242
http://dx.doi.org/10.3390/md21030193
_version_ 1785015084944195584
author Akram, Wasim
Rihan, Mohd
Ahmed, Sakeel
Arora, Swamita
Ahmad, Sameer
Vashishth, Rahul
author_facet Akram, Wasim
Rihan, Mohd
Ahmed, Sakeel
Arora, Swamita
Ahmad, Sameer
Vashishth, Rahul
author_sort Akram, Wasim
collection PubMed
description Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds’ cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed.
format Online
Article
Text
id pubmed-10052127
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100521272023-03-30 Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry Akram, Wasim Rihan, Mohd Ahmed, Sakeel Arora, Swamita Ahmad, Sameer Vashishth, Rahul Mar Drugs Review Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds’ cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed. MDPI 2023-03-21 /pmc/articles/PMC10052127/ /pubmed/36976242 http://dx.doi.org/10.3390/md21030193 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Akram, Wasim
Rihan, Mohd
Ahmed, Sakeel
Arora, Swamita
Ahmad, Sameer
Vashishth, Rahul
Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title_full Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title_fullStr Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title_full_unstemmed Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title_short Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry
title_sort marine-derived compounds applied in cardiovascular diseases: submerged medicinal industry
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052127/
https://www.ncbi.nlm.nih.gov/pubmed/36976242
http://dx.doi.org/10.3390/md21030193
work_keys_str_mv AT akramwasim marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry
AT rihanmohd marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry
AT ahmedsakeel marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry
AT aroraswamita marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry
AT ahmadsameer marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry
AT vashishthrahul marinederivedcompoundsappliedincardiovasculardiseasessubmergedmedicinalindustry