Understanding the Mechanisms and Treatment of Heart Failure: Quantitative Systems Pharmacology Models with a Focus on SGLT2 Inhibitors and Sex-Specific Differences

Heart failure (HF), which is a major clinical and public health challenge, commonly develops when the myocardial muscle is unable to pump an adequate amount of blood at typical cardiac pressures to fulfill the body’s metabolic needs, and compensatory mechanisms are compromised or fail to adjust. Tre...

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Detalles Bibliográficos
Autores principales: Ndiaye, Jean François, Nekka, Fahima, Craig, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052171/
https://www.ncbi.nlm.nih.gov/pubmed/36986862
http://dx.doi.org/10.3390/pharmaceutics15031002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052171/
https://www.ncbi.nlm.nih.gov/pubmed/36986862
http://dx.doi.org/10.3390/pharmaceutics15031002

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