Evaluation of Potential In Vitro Recombination Events in Codon Deoptimized FMDV Strains

Codon deoptimization (CD) has been recently used as a possible strategy to derive foot-and-mouth disease (FMD) live-attenuated vaccine (LAV) candidates containing DIVA markers. However, reversion to virulence, or loss of DIVA, from possible recombination with wild-type (WT) strains has yet to be ana...

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Detalles Bibliográficos
Autores principales: Spinard, Edward, Fish, Ian, Azzinaro, Paul A., Rodriguez-Calzada, Monica, Hartwig, Ethan J., Smoliga, George R., Mogulothu, Aishwarya, Arzt, Jonathan, de los Santos, Teresa, Medina, Gisselle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052203/
https://www.ncbi.nlm.nih.gov/pubmed/36992379
http://dx.doi.org/10.3390/v15030670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052203/
https://www.ncbi.nlm.nih.gov/pubmed/36992379
http://dx.doi.org/10.3390/v15030670

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