The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development

[Image: see text] Biocatalysis is a highly valued enabling technology for pharmaceutical research and development as it can unlock synthetic routes to complex chiral motifs with unparalleled selectivity and efficiency. This perspective aims to review recent advances in the pharmaceutical implementat...

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Detalles Bibliográficos
Autores principales: France, Scott P., Lewis, Russell D., Martinez, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052283/
https://www.ncbi.nlm.nih.gov/pubmed/37006753
http://dx.doi.org/10.1021/jacsau.2c00712
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author France, Scott P.
Lewis, Russell D.
Martinez, Carlos A.
author_facet France, Scott P.
Lewis, Russell D.
Martinez, Carlos A.
author_sort France, Scott P.
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description [Image: see text] Biocatalysis is a highly valued enabling technology for pharmaceutical research and development as it can unlock synthetic routes to complex chiral motifs with unparalleled selectivity and efficiency. This perspective aims to review recent advances in the pharmaceutical implementation of biocatalysis across early and late-stage development with a focus on the implementation of processes for preparative-scale syntheses.
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spelling pubmed-100522832023-03-30 The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development France, Scott P. Lewis, Russell D. Martinez, Carlos A. JACS Au [Image: see text] Biocatalysis is a highly valued enabling technology for pharmaceutical research and development as it can unlock synthetic routes to complex chiral motifs with unparalleled selectivity and efficiency. This perspective aims to review recent advances in the pharmaceutical implementation of biocatalysis across early and late-stage development with a focus on the implementation of processes for preparative-scale syntheses. American Chemical Society 2023-02-27 /pmc/articles/PMC10052283/ /pubmed/37006753 http://dx.doi.org/10.1021/jacsau.2c00712 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle France, Scott P.
Lewis, Russell D.
Martinez, Carlos A.
The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title_full The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title_fullStr The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title_full_unstemmed The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title_short The Evolving Nature of Biocatalysis in Pharmaceutical Research and Development
title_sort evolving nature of biocatalysis in pharmaceutical research and development
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052283/
https://www.ncbi.nlm.nih.gov/pubmed/37006753
http://dx.doi.org/10.1021/jacsau.2c00712
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