Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice

The emergence of new immune-evasive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and subvariants outpaces the development of vaccines specific against the dominant circulating strains. In terms of the only accepted immune correlate of protection, the inactivated whole-virion...

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Detalles Bibliográficos
Autores principales: Cai, Jian-Piao, Luo, Cuiting, Wang, Kun, Cao, Hehe, Chen, Lin-Lei, Zhang, Xiaojuan, Han, Yuting, Yin, Feifei, Zhang, Anna Jinxia, Chu, Hin, Yuan, Shuofeng, Kok, Kin-Hang, To, Kelvin Kai-Wang, Chen, Honglin, Chen, Zhiwei, Jin, Dong-Yan, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052291/
https://www.ncbi.nlm.nih.gov/pubmed/36992395
http://dx.doi.org/10.3390/v15030687

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