Pravastatin Improves Colonic and Hepatic Microcirculatory Oxygenation during Sepsis without Affecting Mitochondrial Function and ROS Production in Rats

Microcirculatory and mitochondrial dysfunction are considered the main mechanisms of septic shock. Studies suggest that statins modulate inflammatory response, microcirculation, and mitochondrial function, possibly through their action on peroxisome proliferator-activated receptor alpha (PPAR-α). Th...

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Detalles Bibliográficos
Autores principales: Kuebart, Anne, Gross, Katharina, Ripkens, Jan-Joschua, Tenge, Theresa, Raupach, Annika, Schulz, Jan, Truse, Richard, Hof, Stefan, Marcus, Carsten, Vollmer, Christian, Bauer, Inge, Picker, Olaf, Herminghaus, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052315/
https://www.ncbi.nlm.nih.gov/pubmed/36982530
http://dx.doi.org/10.3390/ijms24065455

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