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Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis

Chronic type B aortic dissection (cTBAD) is a rare but challenging condition that requires individual treatment strategies. Especially the long-term therapy impacts prognosis. In this single-center retrospective study, we evaluated patients with cTBAD in our vascular outpatient clinic over 10 years....

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Autores principales: Mohajeri, Darya, Rammos, Christos, Tsagakis, Konstantinos, Schlosser, Thomas, Ruhparwar, Arjang, Rassaf, Tienush, Jánosi, Rolf Alexander, Lortz, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052347/
https://www.ncbi.nlm.nih.gov/pubmed/36984006
http://dx.doi.org/10.3390/life13030851
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author Mohajeri, Darya
Rammos, Christos
Tsagakis, Konstantinos
Schlosser, Thomas
Ruhparwar, Arjang
Rassaf, Tienush
Jánosi, Rolf Alexander
Lortz, Julia
author_facet Mohajeri, Darya
Rammos, Christos
Tsagakis, Konstantinos
Schlosser, Thomas
Ruhparwar, Arjang
Rassaf, Tienush
Jánosi, Rolf Alexander
Lortz, Julia
author_sort Mohajeri, Darya
collection PubMed
description Chronic type B aortic dissection (cTBAD) is a rare but challenging condition that requires individual treatment strategies. Especially the long-term therapy impacts prognosis. In this single-center retrospective study, we evaluated patients with cTBAD in our vascular outpatient clinic over 10 years. Follow-up consultations included contrast-enhanced, electrocardiogram-triggered, high-resolution CT angiography (CTA) covering the entire aorta. Evaluated characteristics went beyond demographic characteristics combining the treatment approach and the timing and occurrence of potential complications. We analyzed 133 patients in total (n = 92, 69.2% male) with cTBAD with a mean follow-up of 67.7 months. Most of them underwent invasive treatment (n = 102, 76.7%), the majority received thoracic endovascular aortic repair (TEVAR) (n = 82, 61.7%). A total of 80 patients (60.2%) had major complications, whereas over a third was free of complications even after 5 years. Most common complications were progress of dissection and endoleaks, aneurysms of true (TL) and false lumen (FL) were more common in the later time periods. The treatment of cTBAD in terms of timing, therapy approach, and complications is still challenging for the entire aortic team. Nevertheless, the early recognition of complications permits promising treatment options and highlights the importance of frequent follow-up examinations especially within the first years.
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spelling pubmed-100523472023-03-30 Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis Mohajeri, Darya Rammos, Christos Tsagakis, Konstantinos Schlosser, Thomas Ruhparwar, Arjang Rassaf, Tienush Jánosi, Rolf Alexander Lortz, Julia Life (Basel) Article Chronic type B aortic dissection (cTBAD) is a rare but challenging condition that requires individual treatment strategies. Especially the long-term therapy impacts prognosis. In this single-center retrospective study, we evaluated patients with cTBAD in our vascular outpatient clinic over 10 years. Follow-up consultations included contrast-enhanced, electrocardiogram-triggered, high-resolution CT angiography (CTA) covering the entire aorta. Evaluated characteristics went beyond demographic characteristics combining the treatment approach and the timing and occurrence of potential complications. We analyzed 133 patients in total (n = 92, 69.2% male) with cTBAD with a mean follow-up of 67.7 months. Most of them underwent invasive treatment (n = 102, 76.7%), the majority received thoracic endovascular aortic repair (TEVAR) (n = 82, 61.7%). A total of 80 patients (60.2%) had major complications, whereas over a third was free of complications even after 5 years. Most common complications were progress of dissection and endoleaks, aneurysms of true (TL) and false lumen (FL) were more common in the later time periods. The treatment of cTBAD in terms of timing, therapy approach, and complications is still challenging for the entire aortic team. Nevertheless, the early recognition of complications permits promising treatment options and highlights the importance of frequent follow-up examinations especially within the first years. MDPI 2023-03-22 /pmc/articles/PMC10052347/ /pubmed/36984006 http://dx.doi.org/10.3390/life13030851 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mohajeri, Darya
Rammos, Christos
Tsagakis, Konstantinos
Schlosser, Thomas
Ruhparwar, Arjang
Rassaf, Tienush
Jánosi, Rolf Alexander
Lortz, Julia
Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title_full Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title_fullStr Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title_full_unstemmed Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title_short Complications in Patients with Chronic Type B Aortic Dissection (cTBAD)—A Long-Term Analysis
title_sort complications in patients with chronic type b aortic dissection (ctbad)—a long-term analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052347/
https://www.ncbi.nlm.nih.gov/pubmed/36984006
http://dx.doi.org/10.3390/life13030851
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