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Proteochemometric Modeling Identifies Chemically Diverse Norepinephrine Transporter Inhibitors

[Image: see text] Solute carriers (SLCs) are relatively underexplored compared to other prominent protein families such as kinases and G protein-coupled receptors. However, proteins from the SLC family play an essential role in various diseases. One such SLC is the high-affinity norepinephrine trans...

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Detalles Bibliográficos
Autores principales: Bongers, Brandon J., Sijben, Huub J., Hartog, Peter B. R., Tarnovskiy, Andrey, IJzerman, Adriaan P., Heitman, Laura H., van Westen, Gerard J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052348/
https://www.ncbi.nlm.nih.gov/pubmed/36926886
http://dx.doi.org/10.1021/acs.jcim.2c01645