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Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report

Disseminated cutaneous candidiasis is a rare manifestation of candidiasis that arises most commonly from Candida albicans. It is described as a widespread erythematous papulopustular skin infection that typically affects premature newborns or immunocompromised patients. While candidal infections usu...

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Autores principales: Seale, Emily, Spurr, Alison, Teo, Iris, Glassman, Steven J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052466/
https://www.ncbi.nlm.nih.gov/pubmed/37009549
http://dx.doi.org/10.1177/2050313X231160949
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author Seale, Emily
Spurr, Alison
Teo, Iris
Glassman, Steven J
author_facet Seale, Emily
Spurr, Alison
Teo, Iris
Glassman, Steven J
author_sort Seale, Emily
collection PubMed
description Disseminated cutaneous candidiasis is a rare manifestation of candidiasis that arises most commonly from Candida albicans. It is described as a widespread erythematous papulopustular skin infection that typically affects premature newborns or immunocompromised patients. While candidal infections usually respond well to antifungal therapy, the clinical presentation of disseminated cutaneous candidiasis can often mimic a variety of other dermatologic conditions, that can lead to delayed diagnosis and treatment. We present a 67-year-old comorbid male patient with widespread erythema and superficial pustules resembling acute generalized exanthematous pustulosis (AGEP) that was actually an unexpected manifestation of disseminated cutaneous candidiasis. Prompt initiation of a topical and oral antifungal regimen contributed to marked improvement. Given the high frequency of drug eruptions in comorbid patients receiving multiple medications, alternate diagnoses like infections should be included in the differential diagnosis.
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spelling pubmed-100524662023-03-30 Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report Seale, Emily Spurr, Alison Teo, Iris Glassman, Steven J SAGE Open Med Case Rep JCMS Case Report Disseminated cutaneous candidiasis is a rare manifestation of candidiasis that arises most commonly from Candida albicans. It is described as a widespread erythematous papulopustular skin infection that typically affects premature newborns or immunocompromised patients. While candidal infections usually respond well to antifungal therapy, the clinical presentation of disseminated cutaneous candidiasis can often mimic a variety of other dermatologic conditions, that can lead to delayed diagnosis and treatment. We present a 67-year-old comorbid male patient with widespread erythema and superficial pustules resembling acute generalized exanthematous pustulosis (AGEP) that was actually an unexpected manifestation of disseminated cutaneous candidiasis. Prompt initiation of a topical and oral antifungal regimen contributed to marked improvement. Given the high frequency of drug eruptions in comorbid patients receiving multiple medications, alternate diagnoses like infections should be included in the differential diagnosis. SAGE Publications 2023-03-28 /pmc/articles/PMC10052466/ /pubmed/37009549 http://dx.doi.org/10.1177/2050313X231160949 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle JCMS Case Report
Seale, Emily
Spurr, Alison
Teo, Iris
Glassman, Steven J
Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title_full Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title_fullStr Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title_full_unstemmed Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title_short Cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report
title_sort cutaneous candidiasis mimicking acute generalized exanthematous pustulosis: a case report
topic JCMS Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052466/
https://www.ncbi.nlm.nih.gov/pubmed/37009549
http://dx.doi.org/10.1177/2050313X231160949
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