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Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury

OBJECTIVES: Long-term results of hepaticojejunostomy (HJ) for complex bile duct injury (BDI) remain under-reported. The objective of this study was to assess short-term and long-term outcomes of HJ for post-cholecystectomy BDI. METHODS: This was a retrospective cohort study and included patients who...

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Autores principales: Ahmad, Humaid, Zia, Haseeb Haider, Salih, Mohammad, Naseer, Muhammad, Khan, Nusrat Yar, Bhatti, Abu Bakar Hafeez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052492/
https://www.ncbi.nlm.nih.gov/pubmed/36974893
http://dx.doi.org/10.1177/03000605231162444
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author Ahmad, Humaid
Zia, Haseeb Haider
Salih, Mohammad
Naseer, Muhammad
Khan, Nusrat Yar
Bhatti, Abu Bakar Hafeez
author_facet Ahmad, Humaid
Zia, Haseeb Haider
Salih, Mohammad
Naseer, Muhammad
Khan, Nusrat Yar
Bhatti, Abu Bakar Hafeez
author_sort Ahmad, Humaid
collection PubMed
description OBJECTIVES: Long-term results of hepaticojejunostomy (HJ) for complex bile duct injury (BDI) remain under-reported. The objective of this study was to assess short-term and long-term outcomes of HJ for post-cholecystectomy BDI. METHODS: This was a retrospective cohort study and included patients who underwent Roux-en-Y HJ for BDI (n = 87). Short-term (90-day) and long-term morbidity and mortality were assessed. RESULTS: At presentation, 42 (48.2%) patients had E3 or E4 BDI, 27 (31%) patients had vascular injury, and liver resection was performed in 12 (13.7%) patients. The 90-day morbidity was 51.7% (n = 45), and the 90-day mortality was 2.3% (n = 2). The long-term mortality was 3.4% (n = 3). The 10-year estimated stricture-free survival was 95%. The 10-year estimated overall survival rate was 100% in patients who underwent major hepatectomy and 91% in patients who did not. The 10-year estimated overall survival rate was 100% in patients with vasculobiliary injury and was not reached in patients without vascular injury. CONCLUSIONS: Vascular injury with proximal BDI is not uncommon. Excellent long-term outcomes might be achieved with Roux-en-Y HJ for BDI with vascular injury and in patients requiring liver resection.
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spelling pubmed-100524922023-03-30 Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury Ahmad, Humaid Zia, Haseeb Haider Salih, Mohammad Naseer, Muhammad Khan, Nusrat Yar Bhatti, Abu Bakar Hafeez J Int Med Res Retrospective Clinical Research Report OBJECTIVES: Long-term results of hepaticojejunostomy (HJ) for complex bile duct injury (BDI) remain under-reported. The objective of this study was to assess short-term and long-term outcomes of HJ for post-cholecystectomy BDI. METHODS: This was a retrospective cohort study and included patients who underwent Roux-en-Y HJ for BDI (n = 87). Short-term (90-day) and long-term morbidity and mortality were assessed. RESULTS: At presentation, 42 (48.2%) patients had E3 or E4 BDI, 27 (31%) patients had vascular injury, and liver resection was performed in 12 (13.7%) patients. The 90-day morbidity was 51.7% (n = 45), and the 90-day mortality was 2.3% (n = 2). The long-term mortality was 3.4% (n = 3). The 10-year estimated stricture-free survival was 95%. The 10-year estimated overall survival rate was 100% in patients who underwent major hepatectomy and 91% in patients who did not. The 10-year estimated overall survival rate was 100% in patients with vasculobiliary injury and was not reached in patients without vascular injury. CONCLUSIONS: Vascular injury with proximal BDI is not uncommon. Excellent long-term outcomes might be achieved with Roux-en-Y HJ for BDI with vascular injury and in patients requiring liver resection. SAGE Publications 2023-03-28 /pmc/articles/PMC10052492/ /pubmed/36974893 http://dx.doi.org/10.1177/03000605231162444 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Ahmad, Humaid
Zia, Haseeb Haider
Salih, Mohammad
Naseer, Muhammad
Khan, Nusrat Yar
Bhatti, Abu Bakar Hafeez
Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title_full Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title_fullStr Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title_full_unstemmed Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title_short Outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
title_sort outcomes of hepaticojejunostomy for post-cholecystectomy bile duct injury
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052492/
https://www.ncbi.nlm.nih.gov/pubmed/36974893
http://dx.doi.org/10.1177/03000605231162444
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