Harnessing Fc/FcRn Affinity Data from Patents with Different Machine Learning Methods

Monoclonal antibodies are biopharmaceuticals with a very long half-life due to the binding of their Fc portion to the neonatal receptor (FcRn), a pharmacokinetic property that can be further improved through engineering of the Fc portion, as demonstrated by the approval of several new drugs. Many Fc...

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Detalles Bibliográficos
Autores principales: Dumet, Christophe, Pugnière, Martine, Henriquet, Corinne, Gouilleux-Gruart, Valérie, Poupon, Anne, Watier, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052518/
https://www.ncbi.nlm.nih.gov/pubmed/36982796
http://dx.doi.org/10.3390/ijms24065724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052518/
https://www.ncbi.nlm.nih.gov/pubmed/36982796
http://dx.doi.org/10.3390/ijms24065724

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