Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies

Camptothecin (CPT), an alkaloid with potent anticancer activity, is still not used in clinical practice due to its high hydrophobicity, toxicity, and poor active-form stability. To address these shortcomings, our research focuses on the encapsulation of this drug in the poly(amidoamine) (PAMAM) dend...

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Detalles Bibliográficos
Autores principales: Oledzka, Ewa, Paśnik, Klaudia, Domańska, Izabela, Zielińska-Pisklak, Monika, Piotrowska, Urszula, Sobczak, Marcin, Szeleszczuk, Łukasz, Laskowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052527/
https://www.ncbi.nlm.nih.gov/pubmed/36985668
http://dx.doi.org/10.3390/molecules28062696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052527/
https://www.ncbi.nlm.nih.gov/pubmed/36985668
http://dx.doi.org/10.3390/molecules28062696

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