Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi

Chagas disease is an endemic tropical disease caused by the protozoan Trypanosoma cruzi, which affects around 7 million people worldwide, mostly in development countries. The treatment relies on only two available drugs, with severe adverse effects and a limited efficacy. Therefore, the search for n...

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Detalles Bibliográficos
Autores principales: Amaral, Maiara, Varela, Marina T., Kant, Ravi, Christodoulides, Myron, Fernandes, João Paulo S., Tempone, Andre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052702/
https://www.ncbi.nlm.nih.gov/pubmed/36983820
http://dx.doi.org/10.3390/life13030663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052702/
https://www.ncbi.nlm.nih.gov/pubmed/36983820
http://dx.doi.org/10.3390/life13030663

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