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Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi
Chagas disease is an endemic tropical disease caused by the protozoan Trypanosoma cruzi, which affects around 7 million people worldwide, mostly in development countries. The treatment relies on only two available drugs, with severe adverse effects and a limited efficacy. Therefore, the search for n...
Autores principales: | Amaral, Maiara, Varela, Marina T., Kant, Ravi, Christodoulides, Myron, Fernandes, João Paulo S., Tempone, Andre G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052702/ https://www.ncbi.nlm.nih.gov/pubmed/36983820 http://dx.doi.org/10.3390/life13030663 |
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