Cargando…

Neutralization Sensitivity and Evolution of Virus in a Chronic HIV-1 Clade B Infected Patient with Neutralizing Activity against Membrane-Proximal External Region

The membrane-proximal external region (MPER) is a promising HIV-1 vaccine target owing to its linear neutralizing epitopes and highly conserved amino acids. Here, we explored the neutralization sensitivity and investigated the MPER sequences in a chronic HIV-1 infected patient with neutralizing acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Wenqi, Yuan, Zhenzhen, Wang, Zheng, Ren, Li, Li, Dan, Wang, Shuhui, Hao, Yanling, Li, Jing, Shen, Xiuli, Ruan, Yuhua, Shao, Yiming, Liu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052815/ https://www.ncbi.nlm.nih.gov/pubmed/36986419 http://dx.doi.org/10.3390/pathogens12030497

Ejemplares similares

Virus Evolution and Neutralization Sensitivity in an HIV-1 Subtype B′ Infected Plasma Donor with Broadly Neutralizing Activity
por: Hu, Yuanyuan, et al.
Publicado: (2021)

Enhancing HIV-1 Neutralization by Increasing the Local Concentration of Membrane-Proximal External Region-Directed Broadly Neutralizing Antibodies
por: Kim, Soohyun, et al.
Publicado: (2022)

Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41
por: Lai, Rachel P.J., et al.
Publicado: (2011)

Evolution of Neutralization Response in HIV-1 Subtype C-Infected Individuals Exhibiting Broad Cross-Clade Neutralization of HIV-1 Strains
por: Cheedarla, Narayanaiah, et al.
Publicado: (2018)

HIV-1 gp41 Core with Exposed Membrane-Proximal External Region Inducing Broad HIV-1 Neutralizing Antibodies
por: Wang, Ji, et al.
Publicado: (2011)

Neutral Evolution
por: Saitou, Naruya
Publicado: (2013)

Neutral Evolution
por: Saitou, Naruya
Publicado: (2018)

Neutralizing Antibody Responses and Evolution of the Viral Envelope in the Course of HIV-1 Korean Clade B Infection
por: Shin, Bo Gyeong, et al.
Publicado: (2011)

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity
por: Bradley, Todd, et al.
Publicado: (2016)

Inducing Cross-Clade Neutralizing Antibodies against HIV-1 by Immunofocusing
por: Humbert, Michael, et al.
Publicado: (2008)

P04-09. Induction of cross-clade neutralizing antibodies with a prime/boost vaccine strategy focused on a neutralizing epitope
por: Zolla-Pazner, S, et al.
Publicado: (2009)

R5 Clade C SHIV Strains with Tier 1 or 2 Neutralization Sensitivity: Tools to Dissect Env Evolution and to Develop AIDS Vaccines in Primate Models
por: Siddappa, Nagadenahalli B., et al.
Publicado: (2010)

Neutral and Non-Neutral Evolution of Duplicated Genes with Gene Conversion
por: Fawcett, Jeffrey A., et al.
Publicado: (2011)

Neutralization Sensitivity of HIV-1 CRF07_BC From an Untreated Patient With a Focus on Evolution Over Time
por: Wang, Lijie, et al.
Publicado: (2022)

Neutralization sensitivity, fusogenicity, and infectivity of Omicron subvariants
por: Wang, Xue-Jun, et al.
Publicado: (2022)

Optimization of the EC26-2A4 Epitope in the gp41 Membrane Proximal External Region Targeted by Neutralizing Antibodies from an Elite Controller
por: Ringel, Oliver, et al.
Publicado: (2018)

Branching processes and neutral evolution
por: Taïb, Ziad
Publicado: (1992)

Neutral Models of Microbiome Evolution
por: Zeng, Qinglong, et al.
Publicado: (2015)

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells
por: Cohen, Yehuda Z., et al.
Publicado: (2018)

An Efficiently Cleaved HIV-1 Clade C Env Selectively Binds to Neutralizing Antibodies
por: Boliar, Saikat, et al.
Publicado: (2015)

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
por: Kumar, Rajesh, et al.
Publicado: (2021)

Rapid development of cross-clade neutralizing antibody responses after clade B gp120/gp140 protein priming and clade c gp140 protein boosting
por: Spearman, P, et al.
Publicado: (2012)

Early Pro-Inflammatory Signal and T-Cell Activation Associate With Vaccine-Induced Anti-Vaccinia Protective Neutralizing Antibodies
por: Hou, Jue, et al.
Publicado: (2021)

Identification of a novel broadly HIV-1-neutralizing antibody from a CRF01_AE-infected Chinese donor
por: Ju, Bin, et al.
Publicado: (2018)

Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection
por: Wagh, Kshitij, et al.
Publicado: (2016)

A Neutral Model of Transcriptome Evolution
por: Khaitovich, Philipp, et al.
Publicado: (2004)

Molecular clock in neutral protein evolution
por: Wilke, Claus O
Publicado: (2004)

Emergent Neutrality in Adaptive Asexual Evolution
por: Schiffels, Stephan, et al.
Publicado: (2011)

P04-03. Cross-clade neutralization analysis of plasmas from clade B, C and CRF01_AE HIV-infected donors
por: Binley, J, et al.
Publicado: (2009)

Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens
por: Mesa, Kathryn A., et al.
Publicado: (2019)

Recent Progress toward Engineering HIV-1-Specific Neutralizing Monoclonal Antibodies
por: Sun, Ming, et al.
Publicado: (2016)

Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing
por: Zolla-Pazner, Susan, et al.
Publicado: (2006)

Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination
por: Wang, Meiyu, et al.
Publicado: (2021)

Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein
por: van Haaren, M. M., et al.
Publicado: (2021)

Profiling the neutralizing antibody response in chronically HIV-1 CRF07_BC-infected intravenous drug users naïve to antiretroviral therapy
por: Hu, Xintao, et al.
Publicado: (2017)

GAL08, an Uncultivated Group of Acidobacteria, Is a Dominant Bacterial Clade in a Neutral Hot Spring
por: Ruhl, Ilona A., et al.
Publicado: (2022)

Evidence of Neutral Evolution of Mitochondrial DNA in Human Hepatocellular Carcinoma
por: Liu, Qi, et al.
Publicado: (2019)

The Evolution of Galaxies Through the Neutral Hydrogen Window
por: Minchin, Robert, et al.
Publicado: (2008)

Constructive Neutral Evolution 20 Years Later
por: Muñoz-Gómez, Sergio A., et al.
Publicado: (2021)

The origin of RNA interference: Adaptive or neutral evolution?
por: Torri, Alessandro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0ck3ur55o9aftj2hsbfjlh1kbs