Integrated transcriptomics contrasts fatty acid metabolism with hypoxia response in β-cell subpopulations associated with glycemic control

BACKGROUND: Understanding how heterogeneous β-cell function impacts diabetes is imperative for therapy development. Standard single-cell RNA sequencing analysis illuminates some factors driving heterogeneity, but new strategies are required to enhance information capture. RESULTS: We integrate pancr...

Descripción completa

Detalles Bibliográficos
Autores principales: Miranda, Mario A, Macias-Velasco, Juan F, Schmidt, Heather, Lawson, Heather A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052828/
https://www.ncbi.nlm.nih.gov/pubmed/36978008
http://dx.doi.org/10.1186/s12864-023-09232-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052828/
https://www.ncbi.nlm.nih.gov/pubmed/36978008
http://dx.doi.org/10.1186/s12864-023-09232-5

Ejemplares similares