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Integrated transcriptomics contrasts fatty acid metabolism with hypoxia response in β-cell subpopulations associated with glycemic control
BACKGROUND: Understanding how heterogeneous β-cell function impacts diabetes is imperative for therapy development. Standard single-cell RNA sequencing analysis illuminates some factors driving heterogeneity, but new strategies are required to enhance information capture. RESULTS: We integrate pancr...
Autores principales: | Miranda, Mario A, Macias-Velasco, Juan F, Schmidt, Heather, Lawson, Heather A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052828/ https://www.ncbi.nlm.nih.gov/pubmed/36978008 http://dx.doi.org/10.1186/s12864-023-09232-5 |
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