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Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells

BACKGROUND: Despite well-known susceptibilities to other respiratory viral infections, individuals with allergic asthma have shown reduced susceptibility to severe coronavirus disease 2019 (COVID-19). OBJECTIVE: We sought to identify mechanisms whereby type 2 inflammation in the airway protects agai...

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Detalles Bibliográficos
Autores principales: Doni Jayavelu, Naresh, Altman, Matthew C., Benson, Basilin, Dufort, Matthew J., Vanderwall, Elizabeth R., Rich, Lucille M., White, Maria P., Becker, Patrice M., Togias, Alkis, Jackson, Daniel J., Debley, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052850/
https://www.ncbi.nlm.nih.gov/pubmed/37001649
http://dx.doi.org/10.1016/j.jaci.2023.03.021