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Nanotechnology in Cancer Diagnosis and Treatment

Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting capabilities. Additionally, their low toxic effect on...

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Autores principales: Alrushaid, Noor, Khan, Firdos Alam, Al-Suhaimi, Ebtesam Abdullah, Elaissari, Abdelhamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052895/
https://www.ncbi.nlm.nih.gov/pubmed/36986885
http://dx.doi.org/10.3390/pharmaceutics15031025
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author Alrushaid, Noor
Khan, Firdos Alam
Al-Suhaimi, Ebtesam Abdullah
Elaissari, Abdelhamid
author_facet Alrushaid, Noor
Khan, Firdos Alam
Al-Suhaimi, Ebtesam Abdullah
Elaissari, Abdelhamid
author_sort Alrushaid, Noor
collection PubMed
description Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting capabilities. Additionally, their low toxic effect on healthy cells enhances their bioavailability and t-half by allowing them to functionally penetrate the fenestration of epithelium and tissues. These particles have attracted attention in multidisciplinary areas, making them the most promising materials in many biomedical applications, especially in the treatment and diagnosis of various diseases. Today, many drugs are presented or coated with nanoparticles for the direct targeting of tumors or diseased organs without harming normal tissues/cells. Many types of nanoparticles, such as metallic, magnetic, polymeric, metal oxide, quantum dots, graphene, fullerene, liposomes, carbon nanotubes, and dendrimers, have potential applications in cancer treatment and diagnosis. In many studies, nanoparticles have been reported to show intrinsic anticancer activity due to their antioxidant action and cause an inhibitory effect on the growth of tumors. Moreover, nanoparticles can facilitate the controlled release of drugs and increase drug release efficiency with fewer side effects. Nanomaterials such as microbubbles are used as molecular imaging agents for ultrasound imaging. This review discusses the various types of nanoparticles that are commonly used in cancer diagnosis and treatment.
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spelling pubmed-100528952023-03-30 Nanotechnology in Cancer Diagnosis and Treatment Alrushaid, Noor Khan, Firdos Alam Al-Suhaimi, Ebtesam Abdullah Elaissari, Abdelhamid Pharmaceutics Review Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting capabilities. Additionally, their low toxic effect on healthy cells enhances their bioavailability and t-half by allowing them to functionally penetrate the fenestration of epithelium and tissues. These particles have attracted attention in multidisciplinary areas, making them the most promising materials in many biomedical applications, especially in the treatment and diagnosis of various diseases. Today, many drugs are presented or coated with nanoparticles for the direct targeting of tumors or diseased organs without harming normal tissues/cells. Many types of nanoparticles, such as metallic, magnetic, polymeric, metal oxide, quantum dots, graphene, fullerene, liposomes, carbon nanotubes, and dendrimers, have potential applications in cancer treatment and diagnosis. In many studies, nanoparticles have been reported to show intrinsic anticancer activity due to their antioxidant action and cause an inhibitory effect on the growth of tumors. Moreover, nanoparticles can facilitate the controlled release of drugs and increase drug release efficiency with fewer side effects. Nanomaterials such as microbubbles are used as molecular imaging agents for ultrasound imaging. This review discusses the various types of nanoparticles that are commonly used in cancer diagnosis and treatment. MDPI 2023-03-22 /pmc/articles/PMC10052895/ /pubmed/36986885 http://dx.doi.org/10.3390/pharmaceutics15031025 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alrushaid, Noor
Khan, Firdos Alam
Al-Suhaimi, Ebtesam Abdullah
Elaissari, Abdelhamid
Nanotechnology in Cancer Diagnosis and Treatment
title Nanotechnology in Cancer Diagnosis and Treatment
title_full Nanotechnology in Cancer Diagnosis and Treatment
title_fullStr Nanotechnology in Cancer Diagnosis and Treatment
title_full_unstemmed Nanotechnology in Cancer Diagnosis and Treatment
title_short Nanotechnology in Cancer Diagnosis and Treatment
title_sort nanotechnology in cancer diagnosis and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052895/
https://www.ncbi.nlm.nih.gov/pubmed/36986885
http://dx.doi.org/10.3390/pharmaceutics15031025
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