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The Development of Super-Saturated Rebamipide Eye Drops for Enhanced Solubility, Stability, Patient Compliance, and Bioavailability
The present study aimed to develop clear aqueous rebamipide (REB) eye drops to enhance solubility, stability, patient compliance, and bioavailability. For the preparation of a super-saturated 1.5% REB solution, the pH-modification method using NaOH and a hydrophilic polymer was employed. Low-viscosi...
Autores principales: | Jang, Dong-Jin, Lee, Jun Hak, Kim, Da Hun, Kim, Jin-Woo, Koo, Tae-Sung, Cho, Kwan Hyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053044/ https://www.ncbi.nlm.nih.gov/pubmed/36986811 http://dx.doi.org/10.3390/pharmaceutics15030950 |
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