Cargando…

Intraocular siRNA Delivery Mediated by Penetratin Derivative to Silence Orthotopic Retinoblastoma Gene

Gene therapy brings a ray of hope for inherited ocular diseases that may cause severe vision loss and even blindness. However, due to the dynamic and static absorption barriers, it is challenging to deliver genes to the posterior segment of the eye by topical instillation. To circumvent this limitat...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Xin, Fan, Xingyan, Jiang, Kuan, Hu, Yang, Liu, Yu, Lu, Weiyue, Wei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053059/
https://www.ncbi.nlm.nih.gov/pubmed/36986605
http://dx.doi.org/10.3390/pharmaceutics15030745