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MiR-21-5p regulates the dynamic of mitochondria network and rejuvenates the senile phenotype of bone marrow stromal cells (BMSCs) isolated from osteoporotic SAM/P6 mice

BACKGROUND: Progression of senile osteoporosis is associated with deteriorated regenerative potential of bone marrow-derived mesenchymal stem/stromal cells (BMSCs). According to the recent results, the senescent phenotype of osteoporotic cells strongly correlates with impaired regulation of mitochon...

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Detalles Bibliográficos
Autores principales:	Sikora, Mateusz, Śmieszek, Agnieszka, Pielok, Ariadna, Marycz, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053106/ https://www.ncbi.nlm.nih.gov/pubmed/36978118 http://dx.doi.org/10.1186/s13287-023-03271-1

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