Cargando…

Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

BACKGROUND: Detection of appropriate receptor proteins and drug agents are equally important in the case of drug discovery and development for any disease. In this study, an attempt was made to explore colorectal cancer (CRC) causing molecular signatures as receptors and drug agents as inhibitors by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horaira, Md Abu, Islam, Md. Ariful, Kibria, Md. Kaderi, Alam, Md. Jahangir, Kabir, Syed Rashel, Mollah, Md. Nurul Haque
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053149/ https://www.ncbi.nlm.nih.gov/pubmed/36991484 http://dx.doi.org/10.1186/s12920-023-01488-w

Ejemplares similares

Bioinformatics-based investigation on the genetic influence between SARS-CoV-2 infections and idiopathic pulmonary fibrosis (IPF) diseases, and drug repurposing
por: Islam, Md. Ariful, et al.
Publicado: (2023)

Exploring Core Genes by Comparative Transcriptomics Analysis for Early Diagnosis, Prognosis, and Therapies of Colorectal Cancer
por: Islam, Md. Ariful, et al.
Publicado: (2023)

Integrated bioinformatics and statistical approaches to explore molecular biomarkers for breast cancer diagnosis, prognosis and therapies
por: Alam, Md. Shahin, et al.
Publicado: (2022)

Bioinformatics Screening of Potential Biomarkers from mRNA Expression Profiles to Discover Drug Targets and Agents for Cervical Cancer
por: Reza, Md. Selim, et al.
Publicado: (2022)

Meta-Data Analysis to Explore the Hub of the Hub-Genes That Influence SARS-CoV-2 Infections Highlighting Their Pathogenetic Processes and Drugs Repurposing
por: Mosharaf, Md. Parvez, et al.
Publicado: (2022)

Prediction of serine phosphorylation sites mapping on Schizosaccharomyces Pombe by fusing three encoding schemes with the random forest classifier
por: Tasmia, Samme Amena, et al.
Publicado: (2022)

Robust Identification of Differential Gene Expression Patterns from Multiple Transcriptomics Datasets for Early Diagnosis, Prognosis, and Therapies for Breast Cancer
por: Tuly, Khanis Farhana, et al.
Publicado: (2023)

Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug repurposing
por: Mosharaf, Md. Parvez, et al.
Publicado: (2022)

Gene expression profile analysis to discover molecular signatures for early diagnosis and therapies of triple-negative breast cancer
por: Alam, Md Shahin, et al.
Publicado: (2022)

Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis
por: Mosharaf, Md. Parvez, et al.
Publicado: (2022)

A Robust Approach for Identification of Cancer Biomarkers and Candidate Drugs
por: Shahjaman, Md., et al.
Publicado: (2019)

Classification of Functional Metagenomes Recovered from Different Environmental Samples
por: Akond, Zobaer, et al.
Publicado: (2019)

A Comparison on Some Interval Mapping Approaches for QTL Detection
por: Akond, Zobaer, et al.
Publicado: (2019)

Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis
por: Rahman, Md. Rezanur, et al.
Publicado: (2019)

Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated bioinformatics approaches
por: Ahmed, Fee Faysal, et al.
Publicado: (2022)

Genome-wide identification, characterization and phylogenetic analysis of Dicer-like (DCL) gene family in Coffea arabica
por: Parvez Mosharaf, Md, et al.
Publicado: (2019)

Identification of host genomic biomarkers from multiple transcriptomics datasets for diagnosis and therapies of SARS-CoV-2 infections
por: Sarker, Bandhan, et al.
Publicado: (2023)

Robust Co-clustering to Discover Toxicogenomic Biomarkers and Their Regulatory Doses of Chemical Compounds Using Logistic Probabilistic Hidden Variable Model
por: Hasan, Mohammad Nazmol, et al.
Publicado: (2018)

Toxic Dose prediction of Chemical Compounds to Biomarkers using an ANOVA based Gene Expression Analysis
por: Hasan, Mohammad Nazmol, et al.
Publicado: (2018)

Publisher Correction: Robustification of GWAS to explore effective SNPs addressing the challenges of hidden population stratification and polygenic effects
por: Akond, Zobaer, et al.
Publicado: (2021)

Robustification of GWAS to explore effective SNPs addressing the challenges of hidden population stratification and polygenic effects
por: Akond, Zobaer, et al.
Publicado: (2021)

Metadata analysis to explore hub of the hub-genes highlighting their functions, pathways and regulators for cervical cancer diagnosis and therapies
por: Reza, Md. Selim, et al.
Publicado: (2022)

Metabolomic Biomarker Identification in Presence of Outliers and Missing Values
por: Kumar, Nishith, et al.
Publicado: (2017)

Serum and Plasma Metabolomic Biomarkers for Lung Cancer
por: Kumar, Nishith, et al.
Publicado: (2017)

Biomarker Identification from RNA-Seq Data using a Robust Statistical Approach
por: Akond, Zobaer, et al.
Publicado: (2018)

Robust Significance Analysis of Microarrays by Minimum β-Divergence Method
por: Shahjaman, Md., et al.
Publicado: (2017)

Robustification of Naïve Bayes Classifier and Its Application for Microarray Gene Expression Data Analysis
por: Ahmed, Md. Shakil, et al.
Publicado: (2017)

Statistical meta-analysis to investigate the association between the Interleukin-6 (IL-6) gene polymorphisms and cancer risk
por: Harun-Or-Roshid, Md., et al.
Publicado: (2021)

Association of hypoxia inducible factor 1-Alpha gene polymorphisms with multiple disease risks: A comprehensive meta-analysis
por: Harun-Or-Roshid, Md., et al.
Publicado: (2022)

β-composite Interval Mapping for robust QTL analysis
por: Monir, Md. Mamun, et al.
Publicado: (2018)

Comprehensive In Silico Analysis of RNA Silencing-Related Genes and Their Regulatory Elements in Wheat (Triticum aestivum L.)
por: Akond, Zobaer, et al.
Publicado: (2022)

Bioinformatics and system biology approaches to identify pathophysiological impact of COVID-19 to the progression and severity of neurological diseases
por: Rahman, Md Habibur, et al.
Publicado: (2021)

Heavy Metals in the Fish Tenualosa ilisha Hamilton, 1822 in the Padma–Meghna River Confluence: Potential Risks to Public Health
por: Sarker, Md. Jahangir, et al.
Publicado: (2021)

Robust Feature Selection Approach for Patient Classification using Gene Expression Data
por: Shahjaman, Md., et al.
Publicado: (2017)

Effect of Citrus macroptera Fruit Pulp Juice on Alteration of Caspase Pathway Rendering Anti-Proliferative Activity against Ehrlich’s Ascites Carcinoma in Mice
por: Hasan, Md. Mahmudul, et al.
Publicado: (2019)

Bioinformatics and System Biology Techniques to Determine Biomolecular Signatures and Pathways of Prion Disorder
por: Mredul, Md Bazlur Rahman, et al.
Publicado: (2022)

Robustification of Linear Regression and Its Application in Genome-Wide Association Studies
por: Alamin, Md., et al.
Publicado: (2020)

Nutritional profiling of some selected commercially important freshwater and marine water fishes of Bangladesh
por: Ullah, Md. Rahamat, et al.
Publicado: (2022)

The Antioxidative Fraction of White Mulberry Induces Apoptosis through Regulation of p53 and NFκB in EAC Cells
por: Alam, AHM Khurshid, et al.
Publicado: (2016)

Asymptomatic RT-PCR positive COVID-19 patients in orthopaedic pre-operative evaluation during the peak of the second wave
por: Samiul Islam, Md., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_epd1quthp5m6gf2oses5eeol83