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Mitochondrial Heteroplasmy as a Marker for Premature Coronary Artery Disease: Analysis of the Poly-C Tract of the Control Region Sequence

Mitochondrial DNA (mtDNA) differs from the nuclear genome in many aspects: a maternal inheritance pattern; being more prone to acquire somatic de novo mutations, accumulative with age; and the possible coexistence of different mtDNA alleles (heteroplasmy). Mitochondria are key cellular organelles re...

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Detalles Bibliográficos
Autores principales:	Lorca, Rebeca, Aparicio, Andrea, Gómez, Juan, Álvarez-Velasco, Rut, Pascual, Isaac, Avanzas, Pablo, González-Urbistondo, Francisco, Alen, Alberto, Vázquez-Coto, Daniel, González-Fernández, Mar, García-Lago, Claudia, Cuesta-Llavona, Elías, Morís, César, Coto, Eliecer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053235/ https://www.ncbi.nlm.nih.gov/pubmed/36983136 http://dx.doi.org/10.3390/jcm12062133

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