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Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion

The tendency of using weight loss herbal preparations is continuously increasing, especially for the widespread consumption of junk food that is characterized by high calories. Weight loss herbal preparations are considered a type of food supplement product, and, as such, the regulations governing t...

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Autores principales: Al-Thani, Ghanim, Ibrahim, Adel Ehab, Alomairi, Mohammed, Salman, Baher I., Hegazy, Mostafa M., Al-Harrasi, Ahmed, El Deeb, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053313/
https://www.ncbi.nlm.nih.gov/pubmed/36977037
http://dx.doi.org/10.3390/toxics11030272
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author Al-Thani, Ghanim
Ibrahim, Adel Ehab
Alomairi, Mohammed
Salman, Baher I.
Hegazy, Mostafa M.
Al-Harrasi, Ahmed
El Deeb, Sami
author_facet Al-Thani, Ghanim
Ibrahim, Adel Ehab
Alomairi, Mohammed
Salman, Baher I.
Hegazy, Mostafa M.
Al-Harrasi, Ahmed
El Deeb, Sami
author_sort Al-Thani, Ghanim
collection PubMed
description The tendency of using weight loss herbal preparations is continuously increasing, especially for the widespread consumption of junk food that is characterized by high calories. Weight loss herbal preparations are considered a type of food supplement product, and, as such, the regulations governing their quality control might be minimal. These products could be locally formulated in any country or internationally imported. Being non-controlled products, the herbal weight-loss products may contain high levels of elemental impurities that might exceed the permissible ranges. Moreover, these products contribute to the total daily intake (TDI) of such elements, which might represent concerns about their potential toxicological danger. In this research, the elemental contents in such products were investigated. The inductively coupled plasma with optical emission spectrometer (ICP-OES) was used to determine the levels of 15 elemental contents, namely, Na, K, Ca, Mg, Al, Cu, Fe, Li, Mn, As, Co, Cr, Cd, Ni and Pb. The results showed that seven micro-elements, namely Cd, Co, Ni, Cr, Pb, Li and Cu, were either not detectable or at a concentration much lower than their tolerable limits. However, all studied macro-elements (Na, K, Ca and Mg), together with Fe, were found at considerable, yet safe levels. On the other hand, Mn, Al and As contents showed perturbing levels in some of the studied products. Finally, a conclusion was highlighted for the necessity for stricter surveillance of such herbal products.
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spelling pubmed-100533132023-03-30 Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion Al-Thani, Ghanim Ibrahim, Adel Ehab Alomairi, Mohammed Salman, Baher I. Hegazy, Mostafa M. Al-Harrasi, Ahmed El Deeb, Sami Toxics Article The tendency of using weight loss herbal preparations is continuously increasing, especially for the widespread consumption of junk food that is characterized by high calories. Weight loss herbal preparations are considered a type of food supplement product, and, as such, the regulations governing their quality control might be minimal. These products could be locally formulated in any country or internationally imported. Being non-controlled products, the herbal weight-loss products may contain high levels of elemental impurities that might exceed the permissible ranges. Moreover, these products contribute to the total daily intake (TDI) of such elements, which might represent concerns about their potential toxicological danger. In this research, the elemental contents in such products were investigated. The inductively coupled plasma with optical emission spectrometer (ICP-OES) was used to determine the levels of 15 elemental contents, namely, Na, K, Ca, Mg, Al, Cu, Fe, Li, Mn, As, Co, Cr, Cd, Ni and Pb. The results showed that seven micro-elements, namely Cd, Co, Ni, Cr, Pb, Li and Cu, were either not detectable or at a concentration much lower than their tolerable limits. However, all studied macro-elements (Na, K, Ca and Mg), together with Fe, were found at considerable, yet safe levels. On the other hand, Mn, Al and As contents showed perturbing levels in some of the studied products. Finally, a conclusion was highlighted for the necessity for stricter surveillance of such herbal products. MDPI 2023-03-16 /pmc/articles/PMC10053313/ /pubmed/36977037 http://dx.doi.org/10.3390/toxics11030272 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Thani, Ghanim
Ibrahim, Adel Ehab
Alomairi, Mohammed
Salman, Baher I.
Hegazy, Mostafa M.
Al-Harrasi, Ahmed
El Deeb, Sami
Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title_full Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title_fullStr Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title_full_unstemmed Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title_short Toxic Elemental Impurities in Herbal Weight Loss Supplements; A Study Using ICP-OES Microwave-Assisted Digestion
title_sort toxic elemental impurities in herbal weight loss supplements; a study using icp-oes microwave-assisted digestion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053313/
https://www.ncbi.nlm.nih.gov/pubmed/36977037
http://dx.doi.org/10.3390/toxics11030272
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