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Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models

BACKGROUND: Previous studies have shown a close association between an altered immune system and Parkinson's disease (PD). Neuroinflammation inhibition may be an effective measure to prevent PD. Recently, numerous reports have highlighted the potential of hydroxy-carboxylic acid receptor 2 (HCA...

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Detalles Bibliográficos
Autores principales: He, Dewei, Fu, Shoupeng, Ye, Bojian, Wang, Hefei, He, Yuan, Li, Zhe, Li, Jie, Gao, Xiyu, Liu, Dianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053461/
https://www.ncbi.nlm.nih.gov/pubmed/36991440
http://dx.doi.org/10.1186/s12974-023-02762-5