Cargando…

Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models

BACKGROUND: Previous studies have shown a close association between an altered immune system and Parkinson's disease (PD). Neuroinflammation inhibition may be an effective measure to prevent PD. Recently, numerous reports have highlighted the potential of hydroxy-carboxylic acid receptor 2 (HCA...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Dewei, Fu, Shoupeng, Ye, Bojian, Wang, Hefei, He, Yuan, Li, Zhe, Li, Jie, Gao, Xiyu, Liu, Dianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053461/ https://www.ncbi.nlm.nih.gov/pubmed/36991440 http://dx.doi.org/10.1186/s12974-023-02762-5

Ejemplares similares

Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson’s Disease
por: He, Dewei, et al.
Publicado: (2022)

Echinocystic Acid Inhibits Inflammation and Exerts Neuroprotective Effects in MPTP-Induced Parkinson’s Disease Model Mice
por: He, Dewei, et al.
Publicado: (2022)

Camptothecin Regulates Microglia Polarization and Exerts Neuroprotective Effects via Activating AKT/Nrf2/HO-1 and Inhibiting NF-κB Pathways In Vivo and In Vitro
por: He, Dewei, et al.
Publicado: (2021)

Tubeimoside I Protects Dopaminergic Neurons Against Inflammation-Mediated Damage in Lipopolysaccharide (LPS)-Evoked Model of Parkinson’s Disease in Rats
por: He, Dewei, et al.
Publicado: (2018)

Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis
por: Liu, Bingrun, et al.
Publicado: (2019)

Corrigendum: Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis
por: Liu, Bingrun, et al.
Publicado: (2020)

Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson’s Disease Models
por: Huang, Bingxu, et al.
Publicado: (2017)

Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis
por: Huang, Bingxu, et al.
Publicado: (2018)

α-Cyperone Attenuates H(2)O(2)-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2
por: Huang, Bingxu, et al.
Publicado: (2020)

Chromosomal Location of HCA1 and HCA2, Hybrid Chlorosis Genes in Rice
por: Ichitani, Katsuyuki, et al.
Publicado: (2012)

Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson’s Disease in Rats
por: Chen, Guangxin, et al.
Publicado: (2017)

Updates on Antiobesity Effect of Garcinia Origin (−)-HCA
por: Chuah, Li Oon, et al.
Publicado: (2013)

Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways
por: Chen, Guangxin, et al.
Publicado: (2018)

Induction of HCA587-Specific Antitumor Immunity with HCA587 Protein Formulated with CpG and ISCOM in Mice
por: Chen, Juanjuan, et al.
Publicado: (2012)

Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein
por: Liu, Songqi, et al.
Publicado: (2021)

Hypertension-related, calcium-regulated gene (HCaRG/COMMD5) and kidney diseases: HCaRG accelerates tubular repair
por: Matsuda, Hiroyuki, et al.
Publicado: (2014)

Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
por: Gallardo-Fernández, Marta, et al.
Publicado: (2019)

Overexpression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo
por: Mahmoud, Salma, et al.
Publicado: (2016)

Role of HCA(2) in Regulating Intestinal Homeostasis and Suppressing Colon Carcinogenesis
por: Li, Zhuoyue, et al.
Publicado: (2021)

Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures
por: Malek, Natalia, et al.
Publicado: (2015)

Microglial cell dysregulation in brain aging and neurodegeneration
por: von Bernhardi, Rommy, et al.
Publicado: (2015)

Microglial Potassium Channels: From Homeostasis to Neurodegeneration
por: Cocozza, Germana, et al.
Publicado: (2021)

Microglial Extracellular Vesicles as Vehicles for Neurodegeneration Spreading
por: Aires, Inês Dinis, et al.
Publicado: (2021)

Red Meat and Colorectal Cancer: Exploring the Potential HCA Connection
por: Potera, Carol
Publicado: (2016)

Increased Microglial Exosomal miR-124-3p Alleviates Neurodegeneration and Improves Cognitive Outcome after rmTBI
por: Ge, Xintong, et al.
Publicado: (2020)

Alleviating neurodegeneration in Drosophila models of PolyQ diseases
por: Long, Zhe, et al.
Publicado: (2014)

Screening of Different Organs of Rats for HCA2 Receptor mRNA
por: Shomali, Tahoora, et al.
Publicado: (2014)

Production of Hydroxycarboxylic Acid Receptor 3 (HCA(3)) Ligands by Bifidobacterium
por: Sakurai, Takuma, et al.
Publicado: (2021)

Phosphoinositides: Roles in the Development of Microglial-Mediated Neuroinflammation and Neurodegeneration
por: Ernest James Phillips, Thomas, et al.
Publicado: (2021)

Ginkgolide B alleviates the inflammatory response and attenuates the activation of LPS-induced BV2 cells in vitro and in vivo
por: Sun, Miaoxuan, et al.
Publicado: (2021)

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice
por: Yan, Aijuan, et al.
Publicado: (2019)

Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies
por: Asraf, Keren, et al.
Publicado: (2018)

Parkin regulates microglial NLRP3 and represses neurodegeneration in Parkinson's disease
por: Yan, Yi‐Qun, et al.
Publicado: (2023)

Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplication
por: Bonnart, Chrystelle, et al.
Publicado: (2012)

Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration
por: Morshed, Nader, et al.
Publicado: (2020)

Structural insights into the human niacin receptor HCA2-G(i) signalling complex
por: Yang, Yang, et al.
Publicado: (2023)

Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
por: Yang, Longhe, et al.
Publicado: (2020)

Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration
por: Ding, Xin, et al.
Publicado: (2021)

P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo
por: Gu, Chao, et al.
Publicado: (2018)

Farrerol Relieve Lipopolysaccharide (LPS)-Induced Mastitis by Inhibiting AKT/NF-κB p65, ERK1/2 and P38 Signaling Pathway
por: Li, Yanwei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ivgc5p2v97q2do0962n4jjaa6s