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Metabolic correlates to critical speed in murine models of sickle cell disease

Introduction: Exercise intolerance is a common clinical manifestation in patients with sickle cell disease (SCD), though the mechanisms are incompletely understood. Methods: Here we leverage a murine mouse model of sickle cell disease, the Berkeley mouse, to characterize response to exercise via det...

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Detalles Bibliográficos
Autores principales: Cendali, Francesca I., Nemkov, Travis, Lisk, Christina, Lacroix, Ian S., Nouraie, Seyed-Mehdi, Zhang, Yingze, Gordeuk, Victor R., Buehler, Paul W., Irwin, David, D’Alessandro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053510/
https://www.ncbi.nlm.nih.gov/pubmed/37007990
http://dx.doi.org/10.3389/fphys.2023.1151268