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Polygenic risk score prediction of multiple sclerosis in individuals of South Asian ancestry

Polygenic risk scores aggregate an individual’s burden of risk alleles to estimate the overall genetic risk for a specific trait or disease. Polygenic risk scores derived from genome-wide association studies of European populations perform poorly for other ancestral groups. Given the potential for f...

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Detalles Bibliográficos
Autores principales:	Breedon, Joshua R, Marshall, Charles R, Giovannoni, Gavin, van Heel, David A, Dobson, Ruth, Jacobs, Benjamin M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053643/ https://www.ncbi.nlm.nih.gov/pubmed/37006331 http://dx.doi.org/10.1093/braincomms/fcad041

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