Attenuation of Ventilation-Enhanced Epithelial–Mesenchymal Transition through the Phosphoinositide 3-Kinase-γ in a Murine Bleomycin-Induced Acute Lung Injury Model

Mechanical ventilation (MV) used in patients with acute lung injury (ALI) induces lung inflammation and causes fibroblast proliferation and excessive collagen deposition—a process termed epithelial–mesenchymal transition (EMT). Phosphoinositide 3-kinase-γ (PI3K-γ) is crucial in modulating EMT during...

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Detalles Bibliográficos
Autores principales: Li, Li-Fu, Yu, Chung-Chieh, Huang, Chih-Yu, Wu, Huang-Pin, Chu, Chien-Ming, Liu, Ping-Chi, Liu, Yung-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053679/
https://www.ncbi.nlm.nih.gov/pubmed/36982609
http://dx.doi.org/10.3390/ijms24065538

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