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BBB-on-a-chip with integrated micro-TEER for permeability evaluation of multi-functionalized gold nanorods against Alzheimer’s disease

BACKGROUND: The lack of predictive models that mimic the blood–brain barrier (BBB) hinders the development of effective drugs for neurodegenerative diseases. Animal models behave differently from humans, are expensive and have ethical constraints. Organ-on-a-chip (OoC) platforms offer several advant...

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Detalles Bibliográficos
Autores principales:	Palma-Florez, Sujey, López-Canosa, Adrián, Moralez-Zavala, Francisco, Castaño, Oscar, Kogan, Marcelo J., Samitier, Josep, Lagunas, Anna, Mir, Mònica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053726/ https://www.ncbi.nlm.nih.gov/pubmed/36978078 http://dx.doi.org/10.1186/s12951-023-01798-2

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