HMGA1 augments palbociclib efficacy via PI3K/mTOR signaling in intrahepatic cholangiocarcinoma

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive cancer that is challenging to diagnose at an early stage. Despite recent advances in combination chemotherapy, drug resistance limits the therapeutic value of this regimen. iCCA reportedly harbors high HMGA1 expression and pat...

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Detalles Bibliográficos
Autores principales: Li, Zhipeng, Zhou, Huaxin, Xia, Zhijia, Xia, Tong, Du, Gang, Franziska, Strohmer Dorothee, Li, Xiaoming, Zhai, Xiangyu, Jin, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053751/
https://www.ncbi.nlm.nih.gov/pubmed/36978140
http://dx.doi.org/10.1186/s40364-023-00473-w

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