Identification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers

For patients with type 2 diabetes, metformin is the most often recommended drug. However, there are substantial individual differences in the pharmacological response to metformin. To investigate the effect of transporter polymorphisms on metformin pharmacokinetics in an environment free of confound...

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Detalles Bibliográficos
Autores principales: Saiz-Rodríguez, Miriam, Ochoa, Dolores, Zubiaur, Pablo, Navares-Gómez, Marcos, Román, Manuel, Camargo-Mamani, Paola, Luquero-Bueno, Sergio, Villapalos-García, Gonzalo, Alcaraz, Raquel, Mejía-Abril, Gina, Santos-Mazo, Estefanía, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053761/
https://www.ncbi.nlm.nih.gov/pubmed/36983671
http://dx.doi.org/10.3390/jpm13030489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053761/
https://www.ncbi.nlm.nih.gov/pubmed/36983671
http://dx.doi.org/10.3390/jpm13030489

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